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Multicomponent vaccines
(United States. Patent and Trademark Office, 2010-02-23)
Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
Antibodies recognizing a highly expressed putative antigen of CA-MRSA and methods of use
(United States. Patent and Trademark Office, 2012-02-28)
The present invention provides MSCRAMM® proteins from S. aureus which are putative highly-expressed antigens from methicillin-resistant S. aureus, including communit-associated MRSA (CA-MRSA), and these antigens can thus ...
Staphylococcal immunotherapeutics via donor selection and donor stimulation
(United States. Patent and Trademark Office, 2004-02-17)
A method and composition for the passive immunization of patients infected with or susceptible to infection from Staphylococcus bacteria such as S. aureus and S. epidermidis infection is provided that includes the selection ...
Collagen binding protein compositions and methods of use
(United States. Patent and Trademark Office, 2001-09-11)
Disclosed are the cna gene and cna-derived nucleic acid segments from Staphylococcus aureus, and DNA segments encoding cna from related bacteria. Also disclosed are Col binding protein (CBP) compositions and methods of ...
Collagen-binding proteins from enterococcal bacteria
(United States. Patent and Trademark Office, 2005-06-21)
A collagen-binding MSCRAMM entitled Ace from enterococcal bacteria is provided which was homologous to the ligand-binding region of Cna, the collagen-binding MSCRAMM from Staphylococcus aureus, and which can be utilized ...
Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby
(United States. Patent and Trademark Office, 2009-11-10)
A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can ...
Collagen-binding proteins from enterococcal bacteria
(United States. Patent and Trademark Office, 2009-12-29)
A collagen-binding MSCRAMM entitled Ace from enterococcal bacteria is provided which was homologous to the ligand-binding region of Cna, the collagen-binding MSCRAMM from Staphylococcus aureus, and which can be utilized ...
Decorin binding protein compositions
(United States. Patent and Trademark Office, 2001-05-08)
Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
DbpA compositions
(United States. Patent and Trademark Office, 2001-04-10)
Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
Specific binding sites in collagen for integrins and use thereof
(United States. Patent and Trademark Office, 2009-04-07)
The present invention identified a high affinity binding sequence in collagen type III for the collagen-binding integrin I domains. Provided herein are the methods used to characterize the sequence, the peptides comprising ...