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    Antibodies recognizing a highly expressed putative antigen of CA-MRSA and methods of use

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    8124107.pdf (2.182Mb)
    Date
    2012-02-28
    Author
    Hook, Magnus
    Labandeira-rey, Maria
    Bowden, Gabriela M.
    Metadata
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    Abstract
    The present invention provides MSCRAMM® proteins from S. aureus which are putative highly-expressed antigens from methicillin-resistant S. aureus, including communit-associated MRSA (CA-MRSA), and these antigens can thus be utilized in methods of generating antibodies capable of binding these antigens which can be useful in methods of treating or preventing infection from MRSA. The present invention is directed to these proteins, antibodies capable of binding these proteins, methods of generating said antibodies, nucleic acids coding for said proteins, and pharmaceutical compositions or vaccines which include the proteins or antibodies of the present invention in combination with a pharmaceutically acceptable vehicle, carrier or excipient.
    URI
    http://hdl.handle.net/1969.1/176980
    Subject
    424/243.1
    424/190.1
    424/235.1
    424/236.1
    424/237.1
    530/350
    C07K 14/31
    A61P 31/04
    A61K 39/00
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    • Texas A&M University Patents
    Citation
    Hook, Magnus; Labandeira-rey, Maria; Bowden, Gabriela M. (2012). Antibodies recognizing a highly expressed putative antigen of CA-MRSA and methods of use. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from http : / /hdl .handle .net /1969 .1 /176980.

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