Now showing items 1-18 of 18

    • Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby 

      Hook, Magnus; Xu, Yi; Sillanpaa, Jouko V.; Sthanam, Narayana; Ponnuraj, Karthe; Patti, Joseph M.; Hutchins, Jeff T.; Hall, Andrea; Bowden, Maria G. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2009-11-10)
      A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can ...
    • Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby 

      Hook, Magnus; Xu, Yi; Sillanpaa, Jouko V.; Sthanam, Narayana; Ponnuraj, Karthe; Patti, Joseph M.; Hutchins, Jeff T.; Hall, Andrea; Bowden, Maria G. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2010-12-14)
      A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can ...
    • Collagen binding protein compositions and methods of use 

      Hook, Magnus; Patti, Joseph M.; House-Pompeo, Karen; Sthanam, Narayana; Symersky, Jindrich (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-09-11)
      Disclosed are the cna gene and cna-derived nucleic acid segments from Staphylococcus aureus, and DNA segments encoding cna from related bacteria. Also disclosed are Col binding protein (CBP) compositions and methods of ...
    • Cross-reactive displacing antibodies from collagen-binding proteins and method of identification and use 

      Hook, Magnus; Xu, Yi; Speziale, Pietro; Visal, Livia; Casolini, Fabrizia; Patti, Joseph M.; Patel, Pratiksha; Domanski, Paul (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2007-07-10)
      Antibodies to the CNA protein and to other regions from the collagen binding domain, including domain CNA19, are provided, and antibodies produced in this manner have been shown to be cross reactive to both Staphylococcus ...
    • Extracellular matrix-binding proteins from staphylococcus aureus 

      Patti, Joseph M.; Foster, Timothy J.; Josefsson, Elisabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-01-20)
      Isolated extracellular matrix-binding proteins, designated ClfB, SdrC, SdrD and SdrE, and their corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or ...
    • Extracellular matrix-binding proteins from Staphylococcus aureus 

      Patti, Joseph M.; Foster, Timothy J.; Josefsson, Elisabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2008-06-03)
      Isolated extracellular matrix-binding proteins, designated ClfB, SdrC, SdrD and SdrE, and their corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or ...
    • Fibronectin binding protein compositions and methods of use 

      Hook, Magnus; Patti, Joseph M.; House-pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2006-10-31)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
    • Fibronectin binding protein compositions and methods of use 

      Hook,Magnus; Patti, Joseph M.; House-Pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-02-03)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
    • MHC II analog from Staphylococcus aureus 

      Hook, Magnus; Jonsson, Klas; Patti, Joseph M.; Gurusiddappa, Sivashankarappa (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 1997-07-15)
      Staphylococcus aureus can bind a number of different extracellular matrix proteins. Recent studies have shown that one particular Staphylococcus protein has the capacity of binding several different matrix proteins. The ...
    • Monoclonal antibodies recognizing a coagulase-negative staphylococcal protein 

      Patti, Joseph M.; Hutchins, Jeff T.; Hall, Andrea; Santos, Linda; Bowden, Maria; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2013-07-02)
      Monoclonal antibodies which can bind to the SdrF protein of Staphylococcus epidermidis are provided which can be useful in the treatment and protection against infection from staphylococcal bacteria such as Staphylococcus ...
    • Multicomponent vaccines 

      Patti, Joseph M.; Foster, Timothy J.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2010-02-23)
      Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
    • Multicomponent vaccines 

      Patti, Joseph M.; Foster, Timothy J.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-03-09)
      Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
    • Multicomponent vaccines 

      Patti, Joseph M.; Foster, Timothy J.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2011-09-13)
      Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
    • SdrC protein from Staphylococcus aureus and diagnostic kits including same 

      Patti, Joseph M.; Foster, Timothy J.; Joseffson, Elizabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2010-10-19)
      An isolated extracellular matrix-binding protein, designated as SdrC and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions ...
    • SDRD protein from Staphylococcus aureus and diagnostic kits including same 

      Patti, Joseph M.; Foster, Timothy J.; Josefsson, Elisabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2010-11-16)
      An isolated extracellular matrix-binding protein, designated as SdrD and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions ...
    • SDRE protein from Staphylococcus aureus and diagnostic kits including same 

      Patti, Joseph M.; Foster, Timothy J.; Josefsson, Elisabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2010-12-21)
      An isolated extracellular matrix-binding protein, designated as SdrE and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions ...
    • Staphylococcal immunotherapeutics via donor selection and donor stimulation 

      Patti, Joseph M.; Foster, Timothy J.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-02-17)
      A method and composition for the passive immunization of patients infected with or susceptible to infection from Staphylococcus bacteria such as S. aureus and S. epidermidis infection is provided that includes the selection ...
    • Treatment of Staphylococcus aureus infections utilizing antibodies that bind to fibronectin binding proteins 

      Hook, Magnus; Patti, Joseph M.; House-pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2012-07-03)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...