Monoclonal antibodies recognizing a coagulase-negative staphylococcal protein
Abstract
Monoclonal antibodies which can bind to the SdrF protein of Staphylococcus epidermidis are provided which can be useful in the treatment and protection against infection from staphylococcal bacteria such as Staphylococcus epidermidis. The monoclonal antibodies of the invention are advantageous in that they can also recognize binding domains and subdomains of the S. epidermidis SdrF protein in addition to the protein itself. Suitable compositions and passive vaccines based on the monoclonal antibodies of the invention, as well as methods for their use, are also provided.
Subject
424/150.1424/130.1
424/139.1
424/141.1
424/142.1
424/165.1
435/7.33
435/975
530/388.1
530/388.15
530/388.4
C07K 16/1271
A61P 31/04
C07K 2317/92
C07K 2317/56
C07K 2317/24
A61K 2039/505
Collections
Citation
Patti, Joseph M.; Hutchins, Jeff T.; Hall, Andrea; Santos, Linda; Bowden, Maria; Hook, Magnus (2013). Monoclonal antibodies recognizing a coagulase-negative staphylococcal protein. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /177034.