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    Monoclonal antibodies recognizing a coagulase-negative staphylococcal protein

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    8475798.pdf (1.999Mb)
    Date
    2013-07-02
    Author
    Patti, Joseph M.
    Hutchins, Jeff T.
    Hall, Andrea
    Santos, Linda
    Bowden, Maria
    Hook, Magnus
    Metadata
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    Abstract
    Monoclonal antibodies which can bind to the SdrF protein of Staphylococcus epidermidis are provided which can be useful in the treatment and protection against infection from staphylococcal bacteria such as Staphylococcus epidermidis. The monoclonal antibodies of the invention are advantageous in that they can also recognize binding domains and subdomains of the S. epidermidis SdrF protein in addition to the protein itself. Suitable compositions and passive vaccines based on the monoclonal antibodies of the invention, as well as methods for their use, are also provided.
    URI
    https://hdl.handle.net/1969.1/177034
    Subject
    424/150.1
    424/130.1
    424/139.1
    424/141.1
    424/142.1
    424/165.1
    435/7.33
    435/975
    530/388.1
    530/388.15
    530/388.4
    C07K 16/1271
    A61P 31/04
    C07K 2317/92
    C07K 2317/56
    C07K 2317/24
    A61K 2039/505
    Collections
    • Texas A&M University Patents
    Citation
    Patti, Joseph M.; Hutchins, Jeff T.; Hall, Andrea; Santos, Linda; Bowden, Maria; Hook, Magnus (2013). Monoclonal antibodies recognizing a coagulase-negative staphylococcal protein. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /177034.

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