SDRE protein from Staphylococcus aureus and diagnostic kits including same
Abstract
An isolated extracellular matrix-binding protein, designated as SdrE and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions thereof are useful for the prevention, inhibition, treatment and diagnosis of S. aureus infection and as scientific research tools. Further, antibodies or antibody fragments to the proteins, peptides, fragments thereof or antigenic portions thereof are also useful for the prevention, inhibition, treatment and diagnosis of S. aureus infection. In particular, the proteins or antibodies thereof may be administered to wounds or used to coat biomaterials to act as blocking agents to prevent or inhibit the binding of S. aureus to wounds or biomaterials.
Subject
530/350435/975
530/387.9
G01N 33/56938
C07K 14/31
A61P 31/12
A61K 39/00
Y10S 530/825
G01N 2469/00
Y10S 435/975
Y10S 530/81
A61K 38/00
Collections
Citation
Patti, Joseph M.; Foster, Timothy J.; Josefsson, Elisabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (2010). SDRE protein from Staphylococcus aureus and diagnostic kits including same. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /176944.