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Now showing items 11-20 of 38
DbpA compositions
(United States. Patent and Trademark Office, 2001-04-10)
Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
Extracellular matrix-binding proteins from staphylococcus aureus
(United States. Patent and Trademark Office, 2004-01-20)
Isolated extracellular matrix-binding proteins, designated ClfB, SdrC, SdrD and SdrE, and their corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or ...
Crystal structure of Staphylococcus aureus clumping factor A in complex with fibrinogen derived peptide and uses thereof
(United States. Patent and Trademark Office, 2012-10-02)
The present invention provides a method for determining the structure of a microbial surface components recognizing adhesive matrix molecule in complex with fibrinogen, by providing a ClfA complexed with a fibrinogen ...
Feline CD86 polypeptides and nucleic acids
(United States. Patent and Trademark Office, 2011-12-06)
The present invention provides isolated and purified DNA encoding feline CD80 (B7-1) ligand, feline CD86 (B7-2) ligand, feline CD28 receptor, or feline CTLA-4 (CD152) receptor, as well as vectors comprising nucleic acid ...
Discovery of the first selective C5A receptor 2 (C5L2/C5AR2) ligands
(United States. Patent and Trademark Office, 2019-05-07)
A method of selectively modulating the activity of C5a receptor 2 (C5aR2). The method includes exposing the receptor to a compound that selectively modulates C5aR2 compared to C5a receptor 1 (C5aR1). In some cases, the ...
Fibronectin binding protein compositions and methods of use
(United States. Patent and Trademark Office, 2004-02-03)
Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
HSP20 inhibits amyloidogenesis and neurotoxicity
(United States. Patent and Trademark Office, 2014-04-29)
The present invention compositions and methods of using at least a portions of an isolated and purified α-crystallin polypeptide that includes one or more β-pleated sheets and that prevents neurotoxicity and amyloidogenesis.
SDRD protein from Staphylococcus aureus and diagnostic kits including same
(United States. Patent and Trademark Office, 2010-11-16)
An isolated extracellular matrix-binding protein, designated as SdrD and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions ...
Fibronectin binding protein compositions and methods of use
(United States. Patent and Trademark Office, 2006-10-31)
Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
Method of preventing T cell-mediated responses by the use of the major histocompatibility complex class II analog protein (map protein) from Staphylococcus aureus
(United States. Patent and Trademark Office, 2006-12-26)
A method of immunomodulating the T cell response in Staphylococcal bacteria is provided wherein an effective amount of the Map protein from Staphylococcus aureus is administered to a host to prevent or suppress the T cell ...