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    Feline CD86 polypeptides and nucleic acids

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    8071738.pdf (5.127Mb)
    Date
    2011-12-06
    Author
    Cochran, Mark D.
    Collisson, Ellen W.
    Choi, In-soo
    Winslow, Barbara J.
    Cochran, Mark D.
    Metadata
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    Abstract
    The present invention provides isolated and purified DNA encoding feline CD80 (B7-1) ligand, feline CD86 (B7-2) ligand, feline CD28 receptor, or feline CTLA-4 (CD152) receptor, as well as vectors comprising nucleic acid encoding feline CD80, feline CD86, feline CD28, or feline CTLA-4. The present invention provides a host cells transformed with CD80-encoding vectors, CD86-encoding vectors, CD28-encoding vectors, or CTLA-4-encoding vectors. The invention provides polypeptides encoded by the nucleic acid of feline CD80, feline CD86, feline CD28, or feline CTLA-4. The present invention provides a vaccine comprising an effective amount of polypeptides encoded by the nucleic acid of feline CD80, feline CD86, feline CD28, or feline CTLA-4. The present invention also provides vaccines which further comprise immunogens derived from pathogens. The invention provides for vaccines capable of enhancing an immune response. The invention also provides for vaccines capable of suppressing and immune response.
    URI
    https://hdl.handle.net/1969.1/176966
    Subject
    536/23.1
    435/320.1
    530/350
    C07K 14/70532
    A61P 37/04
    A61K 39/39
    A61P 37/06
    A61K 2039/55516
    A61K 38/00
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    • Texas A&M University Patents
    Citation
    Cochran, Mark D.; Collisson, Ellen W.; Choi, In-soo; Winslow, Barbara J.; Cochran, Mark D. (2011). Feline CD86 polypeptides and nucleic acids. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /176966.

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