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Now showing items 11-19 of 19
Occidiofungin formations and uses thereof
(United States. Patent and Trademark Office, 2019-04-23)
Disclosed are occidiofungin formulations and uses thereof for the treatment of proliferative disorders, such as cancer. Methods of producing the disclosed occidiofungin formulations are also provided. Further, methods of ...
Perlecan domain V protects, repairs and restores ischemic brain stroke injury and motor function
(United States. Patent and Trademark Office, 2015-07-07)
The disclosed invention relates to the use of perlecan domain V (DV) for the treatment of stroke, traumatic brain injury (TBI) or spinal cord injuries (SCI). In certain embodiments, fusion proteins of DV can be used for ...
Compounds and methods for the treatment of cancer
(United States. Patent and Trademark Office, 2012-07-17)
The present invention provides organic arsenicals which may be used to treat numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia.
Cancer treatment targeting non-coding RNA overexpression
(United States. Patent and Trademark Office, 2015-02-17)
Provided herein are methods directed to modulating the pro-oncogenic effects of noncoding RNAs (ncRNAs) through their interactions with specificity protein transcription factors (SpTFs). In one aspect, the disclosure ...
Compositions and methods related to toll-like receptor-3
(United States. Patent and Trademark Office, 2011-11-29)
The invention relates to compositions and methods related to Toll-like receptor (TLR) polypeptides. In some embodiments, the invention relates to managing TLR3 related diseases. In further embodiments, the invention relates ...
Inhibitors of mycobacterium tuberculosis malate synthase, methods of making and uses thereof
(United States. Patent and Trademark Office, 2014-03-04)
The present invention provides aryl- or heteroaryl-diketo acid compounds effective to inhibit an activity of a Mycobacterial malate synthase enzyme or to inhibit a malate synthase activity in other bacteria having the ...
Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases
(United States. Patent and Trademark Office, 2017-01-17)
The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...
Variants of the lantibiotic MU1140 and other lantibiotics with improved pharmacological properties and structural features
(United States. Patent and Trademark Office, 2018-05-08)
The invention provides improvements of lantibiotics useful for reducing the numbers of microbes or the reproduction of microbes in or on subjects or objects. One embodiment of the invention provides variants of antibiotics ...
Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases
(United States. Patent and Trademark Office, 2017-08-15)
The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...