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Treatment of stroke using domain V of perlecan
(United States. Patent and Trademark Office, 2013-06-18)
The present invention is drawn to methods of stimulating or enhancing angiogenesis in a patient comprising, administering to said patient a therapeutically effective amount of an endorepellin protein, wherein said endorepellin ...
Compositions and methods for drug-sensitization or inhibition of a cancer cell
(United States. Patent and Trademark Office, 2018-01-16)
The disclosure provides rifamycin and rifamycin derivative compositions, including rifabutin and rifabutin derivative compositions able to cause drug-sensitization in a cancer cell or inhibition of a cancer cell. The ...
Compositions and methods for drug sensitization of parasites
(United States. Patent and Trademark Office, 2019-03-12)
Compositions and methods for inhibiting and/or sensitizing or re-sensitizing a parasite to an antiparasitic drug are provided. The compositions can comprise a rifamycin derivative or a pharmaceutically acceptable salt, ...
Occidiofungin formations and uses thereof
(United States. Patent and Trademark Office, 2019-04-23)
Disclosed are occidiofungin formulations and uses thereof for the treatment of proliferative disorders, such as cancer. Methods of producing the disclosed occidiofungin formulations are also provided. Further, methods of ...
Perlecan domain V protects, repairs and restores ischemic brain stroke injury and motor function
(United States. Patent and Trademark Office, 2015-07-07)
The disclosed invention relates to the use of perlecan domain V (DV) for the treatment of stroke, traumatic brain injury (TBI) or spinal cord injuries (SCI). In certain embodiments, fusion proteins of DV can be used for ...
Cancer treatment targeting non-coding RNA overexpression
(United States. Patent and Trademark Office, 2015-02-17)
Provided herein are methods directed to modulating the pro-oncogenic effects of noncoding RNAs (ncRNAs) through their interactions with specificity protein transcription factors (SpTFs). In one aspect, the disclosure ...
Compositions and methods related to toll-like receptor-3
(United States. Patent and Trademark Office, 2011-11-29)
The invention relates to compositions and methods related to Toll-like receptor (TLR) polypeptides. In some embodiments, the invention relates to managing TLR3 related diseases. In further embodiments, the invention relates ...