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Prevention of bacterial growth and biofilm formation by ligands that act on cannabinoidergic systems
(United States. Patent and Trademark Office, 2015-11-24)
A group of antimicrobial compounds shows effectiveness for preventing bacterial growth and bio film formation. In particular, the compounds are effective for preventing the growth of gram-positive bacteria, including ...
Compositions and methods for drug-sensitization or inhibition of a cancer cell
(United States. Patent and Trademark Office, 2015-09-15)
The disclosure provides rifamycin and rifamycin derivative compositions, including rifabutin and rifabutin derivative compositions able to cause drug-sensitization in a cancer cell or inhibition of a cancer cell. The ...
Perlecan domain V protects, repairs and restores ischemic brain stroke injury and motor function
(United States. Patent and Trademark Office, 2015-07-07)
The disclosed invention relates to the use of perlecan domain V (DV) for the treatment of stroke, traumatic brain injury (TBI) or spinal cord injuries (SCI). In certain embodiments, fusion proteins of DV can be used for ...
Cancer treatment targeting non-coding RNA overexpression
(United States. Patent and Trademark Office, 2015-02-17)
Provided herein are methods directed to modulating the pro-oncogenic effects of noncoding RNAs (ncRNAs) through their interactions with specificity protein transcription factors (SpTFs). In one aspect, the disclosure ...