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Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases
(United States. Patent and Trademark Office, 2018-10-23)
The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...
Compositions and methods for drug-sensitization or inhibition of a cancer cell
(United States. Patent and Trademark Office, 2018-01-16)
The disclosure provides rifamycin and rifamycin derivative compositions, including rifabutin and rifabutin derivative compositions able to cause drug-sensitization in a cancer cell or inhibition of a cancer cell. The ...
Variants of the lantibiotic MU1140 and other lantibiotics with improved pharmacological properties and structural features
(United States. Patent and Trademark Office, 2018-05-08)
The invention provides improvements of lantibiotics useful for reducing the numbers of microbes or the reproduction of microbes in or on subjects or objects. One embodiment of the invention provides variants of antibiotics ...