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Staphylococcal immunotherapeutics via donor selection and donor stimulation
(United States. Patent and Trademark Office, 2004-02-17)
A method and composition for the passive immunization of patients infected with or susceptible to infection from Staphylococcus bacteria such as S. aureus and S. epidermidis infection is provided that includes the selection ...
Extracellular matrix-binding proteins from Staphylococcus aureus
(United States. Patent and Trademark Office, 2008-06-03)
Isolated extracellular matrix-binding proteins, designated ClfB, SdrC, SdrD and SdrE, and their corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or ...
Collagen binding protein compositions and methods of use
(United States. Patent and Trademark Office, 2001-09-11)
Disclosed are the cna gene and cna-derived nucleic acid segments from Staphylococcus aureus, and DNA segments encoding cna from related bacteria. Also disclosed are Col binding protein (CBP) compositions and methods of ...
Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby
(United States. Patent and Trademark Office, 2009-11-10)
A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can ...
Extracellular matrix-binding proteins from staphylococcus aureus
(United States. Patent and Trademark Office, 2004-01-20)
Isolated extracellular matrix-binding proteins, designated ClfB, SdrC, SdrD and SdrE, and their corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or ...
Cross-reactive displacing antibodies from collagen-binding proteins and method of identification and use
(United States. Patent and Trademark Office, 2007-07-10)
Antibodies to the CNA protein and to other regions from the collagen binding domain, including domain CNA19, are provided, and antibodies produced in this manner have been shown to be cross reactive to both Staphylococcus ...
Fibronectin binding protein compositions and methods of use
(United States. Patent and Trademark Office, 2004-02-03)
Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
Multicomponent vaccines
(United States. Patent and Trademark Office, 2004-03-09)
Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
Fibronectin binding protein compositions and methods of use
(United States. Patent and Trademark Office, 2006-10-31)
Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...