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Antibodies recognizing a highly expressed putative antigen of CA-MRSA and methods of use
(United States. Patent and Trademark Office, 2012-02-28)
The present invention provides MSCRAMM® proteins from S. aureus which are putative highly-expressed antigens from methicillin-resistant S. aureus, including communit-associated MRSA (CA-MRSA), and these antigens can thus ...
Collagen binding protein compositions and methods of use
(United States. Patent and Trademark Office, 2001-09-11)
Disclosed are the cna gene and cna-derived nucleic acid segments from Staphylococcus aureus, and DNA segments encoding cna from related bacteria. Also disclosed are Col binding protein (CBP) compositions and methods of ...
MHC II analog from Staphylococcus aureus
(United States. Patent and Trademark Office, 1997-07-15)
Staphylococcus aureus can bind a number of different extracellular matrix proteins. Recent studies have shown that one particular Staphylococcus protein has the capacity of binding several different matrix proteins. The ...
Crystal structure of Staphylococcus aureus clumping factor A in complex with fibrinogen derived peptide and uses thereof
(United States. Patent and Trademark Office, 2012-10-02)
The present invention provides a method for determining the structure of a microbial surface components recognizing adhesive matrix molecule in complex with fibrinogen, by providing a ClfA complexed with a fibrinogen ...
Fibronectin binding protein compositions and methods of use
(United States. Patent and Trademark Office, 2006-10-31)
Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
Method of preventing T cell-mediated responses by the use of the major histocompatibility complex class II analog protein (map protein) from Staphylococcus aureus
(United States. Patent and Trademark Office, 2006-12-26)
A method of immunomodulating the T cell response in Staphylococcal bacteria is provided wherein an effective amount of the Map protein from Staphylococcus aureus is administered to a host to prevent or suppress the T cell ...
Treatment of Staphylococcus aureus infections utilizing antibodies that bind to fibronectin binding proteins
(United States. Patent and Trademark Office, 2012-07-03)
Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
Crystal structure of Staphylococcus aureus clumping factor A in complex with fibrinogen derived peptide and uses thereof
(United States. Patent and Trademark Office, 2021-06-22)
The present invention discloses crystal structure of Staphylococcus aureus Clumping factor A (ClfA) in complex with fibrinogen (Fg) derived peptide. Also, the present invention also discloses the use of this structure in ...