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Feline CTLA-4 nucleic acid and polypeptides
(United States. Patent and Trademark Office, 2010-06-29)
The present invention provides isolated and purified DNA encoding feline CD80 (B7-1) ligand, feline CD86 (B7-2) ligand, feline CD28 receptor, or feline CTLA-4 (CD152) receptor, as well as vectors comprising nucleic acid ...
Prevention of bacterial growth and biofilm formation by ligands that act on cannabinoidergic systems
(United States. Patent and Trademark Office, 2015-11-24)
A group of antimicrobial compounds shows effectiveness for preventing bacterial growth and bio film formation. In particular, the compounds are effective for preventing the growth of gram-positive bacteria, including ...
Methods and constructs for producing transgenic plants and methods of recovering expressed proteins
(United States. Patent and Trademark Office, 2010-10-19)
This disclosure relates to a regulatory element useful for genetically engineering sugarcane or other monocots, to the transformation of the monocots with the regulatory element so that they produce a desired product, and ...
Crystal structure of Staphylococcus aureus clumping factor A in complex with fibrinogen derived peptide and uses thereof
(United States. Patent and Trademark Office, 2012-10-02)
The present invention provides a method for determining the structure of a microbial surface components recognizing adhesive matrix molecule in complex with fibrinogen, by providing a ClfA complexed with a fibrinogen ...
Feline CD86 polypeptides and nucleic acids
(United States. Patent and Trademark Office, 2011-12-06)
The present invention provides isolated and purified DNA encoding feline CD80 (B7-1) ligand, feline CD86 (B7-2) ligand, feline CD28 receptor, or feline CTLA-4 (CD152) receptor, as well as vectors comprising nucleic acid ...
Discovery of the first selective C5A receptor 2 (C5L2/C5AR2) ligands
(United States. Patent and Trademark Office, 2019-05-07)
A method of selectively modulating the activity of C5a receptor 2 (C5aR2). The method includes exposing the receptor to a compound that selectively modulates C5aR2 compared to C5a receptor 1 (C5aR1). In some cases, the ...
HSP20 inhibits amyloidogenesis and neurotoxicity
(United States. Patent and Trademark Office, 2014-04-29)
The present invention compositions and methods of using at least a portions of an isolated and purified α-crystallin polypeptide that includes one or more β-pleated sheets and that prevents neurotoxicity and amyloidogenesis.
SDRD protein from Staphylococcus aureus and diagnostic kits including same
(United States. Patent and Trademark Office, 2010-11-16)
An isolated extracellular matrix-binding protein, designated as SdrD and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions ...
Treatment of Staphylococcus aureus infections utilizing antibodies that bind to fibronectin binding proteins
(United States. Patent and Trademark Office, 2012-07-03)
Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby
(United States. Patent and Trademark Office, 2010-12-14)
A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can ...