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Vaccine vectors and methods of enhancing immune responses
(United States. Patent and Trademark Office, 2015-02-17)
Provided herein are vaccine vectors including an antigenic polypeptide and an HMGB1 polypeptide present on the surface of the vaccine vector. Compositions comprising the vaccine vectors are also provided and include a ...
Decorin binding protein essential peptides and methods of use
(United States. Patent and Trademark Office, 2003-02-11)
Borrelia burgdorferi, the causative agent of Lyme disease, expresses on its surface a decorin binding protein, DbpA and DbpB. Lysine residues necessary for DbpA binding to decorin and DbpA peptides containing these critical ...
Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby
(United States. Patent and Trademark Office, 2010-12-14)
A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can ...
Decorin binding protein compositions and methods of use
(United States. Patent and Trademark Office, 2001-06-19)
Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...