Browsing by Subject "A61K 38/00"

Now showing items 21-38 of 38

    • HSP20 inhibits amyloidogenesis and neurotoxicity 
      Ficht, Allison; Good, Theresa; Carson, Kenneth; Lee, Sungmun (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2016-04-26)
      The present invention compositions and methods of using at least a portions of an isolated and purified α-crystallin polypeptide that includes one or more β-pleated sheets and that prevents neurotoxicity and amyloidogenesis.
    • HSP20 inhibits amyloidogenesis and neurotoxicity 
      Ficht, Allison; Good, Theresa; Carson, Kenneth; Lee, Sungmun (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2017-10-31)
      The present invention compositions and methods of using at least a portions of an isolated and purified α-crystallin polypeptide that includes one or more β-pleated sheets and that prevents neurotoxicity and amyloidogenesis.
    • Method of preventing T cell-mediated responses by the use of the major histocompatibility complex class II analog protein (map protein) from Staphylococcus aureus 
      Brown, Eric; Lee, Lawrence; Hook, Magnus (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2006-12-26)
      A method of immunomodulating the T cell response in Staphylococcal bacteria is provided wherein an effective amount of the Map protein from Staphylococcus aureus is administered to a host to prevent or suppress the T cell ...
    • Method to produce granulocyte colony stimulating factor from immortalized avian T lymphocytes and method to produce immortalized cells 
      Kogut, Michael H.; DeLoach, John R.; Stanker, Larry H.; Moyes, Rita B.; Hargis, Billy M. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 1997-11-25)
      Immortal avian T lymphocyte cell lines which produce and secrete immune lymphokines are disclosed. These cell lines may be produced from T cells recovered from fowl which have been hyperimmunized in vivo. The activated T ...
    • Methods and constructs for producing transgenic plants and methods of recovering expressed proteins 
      Mirkov, Erik T.; Paterson, Andrew; Yang, Meizhu (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2010-10-19)
      This disclosure relates to a regulatory element useful for genetically engineering sugarcane or other monocots, to the transformation of the monocots with the regulatory element so that they produce a desired product, and ...
    • Methods and constructs for producing transgenic plants and methods of recovering expressed proteins 
      Mirkov, Erik T.; Monclin, Jean P.; Barrilleaux, Adam; Irvine, James E.; Moonan, Francis (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2012-08-28)
      This invention relates to a regulatory element useful for genetically engineering sugarcane or other monocots, to the transformation of the monocots with the regulatory element so that they produce a desired product, and ...
    • Modified lantibiotics and methods of making and using the modified lantibiotics 
      Smith, James L.; Escano, Jerome (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2020-03-03)
      The subject invention pertains to a modified lantibiotic containing an intact cysteine at the C-terminus, particularly, a cysteine that is not decarboxylated and that contains a free carboxyl group. Derivatives of the ...
    • Modified lantibiotics and methods of making and using the modified lantibiotics 
      Smith, James L.; Escano, Jerome (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2022-01-18)
      The subject invention pertains to a modified lantibiotic containing an intact cysteine at the C-terminus, particularly, a cysteine that is not decarboxylated and that contains a free carboxyl group. Derivatives of the ...
    • Modulators Of Melanocortin Receptors For The Treatment Of Depression And Anxiety 
      Hruby, Victor J.; Cai, Minying; Morgan, Caurnel (United States. Patent and Trademark Office; Texas A&M University. Libraries, 1/3/2023)
      Compositions and methods for treating a depressive disorder or an anxiety disorder in a subject in need of such treatment are described herein. A therapeutically effective amount of a composition comprising a melanocortin ...
    • Nucleic acid encoding feline CD86 
      Collisson, Ellen W.; Choi, Insoo; Winslow, Barbara J.; Cochran, Mark D. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2006-07-18)
      The present invention provides isolated and purified DNA encoding feline CD80 (B7-1) ligand, feline CD86 (B7-2) ligand, feline CD28 receptor, or feline CTLA-4 (CD152) receptor, as well as vectors comprising nucleic acid ...
    • Nucleotide and amino acid sequences of asporins 
      Henry, Stephen P.; Hook, Magnus A. O.; Mayne, Richard (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2007-12-04)
      Mouse asporin protein and nucleic acid sequences are disclosed. The protein contains a unique aspartic acid region near the N-terminus. The central domain contains ten leucine rich repeats. Sequences consistent with other ...
    • Prevention of bacterial growth and biofilm formation by ligands that act on cannabinoidergic systems 
      Schetz, John A.; Hoger, Sally A. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2015-11-24)
      A group of antimicrobial compounds shows effectiveness for preventing bacterial growth and bio film formation. In particular, the compounds are effective for preventing the growth of gram-positive bacteria, including ...
    • Regulatory element from a sugarcane proline rich protein and uses thereof 
      Mirkov, Erik T.; Paterson, Andrew; Yang, Meizhu (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2006-11-28)
      This invention relates to a regulatory element useful for genetically engineering sugarcane or other monocots, to the transformation of the monocots with the regulatory element so that they produce a desired product, and ...
    • SdrC protein from Staphylococcus aureus and diagnostic kits including same 
      Patti, Joseph M.; Foster, Timothy J.; Joseffson, Elizabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2010-10-19)
      An isolated extracellular matrix-binding protein, designated as SdrC and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions ...
    • SDRD protein from Staphylococcus aureus and diagnostic kits including same 
      Patti, Joseph M.; Foster, Timothy J.; Josefsson, Elisabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2010-11-16)
      An isolated extracellular matrix-binding protein, designated as SdrD and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions ...
    • SDRE protein from Staphylococcus aureus and diagnostic kits including same 
      Patti, Joseph M.; Foster, Timothy J.; Josefsson, Elisabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2010-12-21)
      An isolated extracellular matrix-binding protein, designated as SdrE and its corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions ...
    • Sugarcane fractioning system 
      Mirkov, Erik T.; Monclin, Jean P.; Barrilleaux, Adam; Irvine, James E.; Moonan, Francis (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2002-11-12)
      A method of extracting and purifying recombinant protein(s) from transgenic sugarcane is disclosed. Fractioning of sugarcane juice that has been extracted from the cane stalks is obtained by using a multiple stage filtering ...
    • Treatment of Staphylococcus aureus infections utilizing antibodies that bind to fibronectin binding proteins 
      Hook, Magnus; Patti, Joseph M.; House-pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2012-07-03)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...