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Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby
(United States. Patent and Trademark Office, 2009-11-10)
A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can ...
Collagen-binding proteins from enterococcal bacteria
(United States. Patent and Trademark Office, 2009-12-29)
A collagen-binding MSCRAMM entitled Ace from enterococcal bacteria is provided which was homologous to the ligand-binding region of Cna, the collagen-binding MSCRAMM from Staphylococcus aureus, and which can be utilized ...
Specific binding sites in collagen for integrins and use thereof
(United States. Patent and Trademark Office, 2009-04-07)
The present invention identified a high affinity binding sequence in collagen type III for the collagen-binding integrin I domains. Provided herein are the methods used to characterize the sequence, the peptides comprising ...
Prokaryotic collagen-like proteins and uses thereof
(United States. Patent and Trademark Office, 2009-06-09)
The present invention provides recombinant triple helical proteins or collagen-like proteins comprising a prokaryotic protein or one or more domains of a prokaryotic protein comprising a collagen-like peptide sequence of ...