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Now showing items 11-20 of 34
Specific binding sites in collagen for integrins and use thereof
(United States. Patent and Trademark Office, 2009-04-07)
The present invention identified a high affinity binding sequence in collagen type III for the collagen-binding integrin I domains. Provided herein are the methods used to characterize the sequence, the peptides comprising ...
Prokaryotic collagen-like proteins and uses thereof
(United States. Patent and Trademark Office, 2009-06-09)
The present invention provides recombinant triple helical proteins or collagen-like proteins comprising a prokaryotic protein or one or more domains of a prokaryotic protein comprising a collagen-like peptide sequence of ...
Designer collagens and use thereof
(United States. Patent and Trademark Office, 2013-12-31)
The present invention identified a recombinant synthetic collagen containing a triple helical backbone protein produced in a prokaryotic expression system where the protein contains at least one ‘inserted’ biologically ...
Prokaryotic collagen-like proteins and uses thereof
(United States. Patent and Trademark Office, 2005-10-11)
The present invention provides recombinant triple helical proteins or collagen-like proteins comprising a prokaryotic protein or one or more domains of a prokaryotic protein comprising a collagen-like peptide sequence of ...
Crystal structure of Staphylococcus aureus clumping factor A in complex with fibrinogen derived peptide and uses thereof
(United States. Patent and Trademark Office, 2012-10-02)
The present invention provides a method for determining the structure of a microbial surface components recognizing adhesive matrix molecule in complex with fibrinogen, by providing a ClfA complexed with a fibrinogen ...
Specific binding sites in collagen for integrins and use thereof
(United States. Patent and Trademark Office, 2019-07-23)
The present invention identified a high affinity binding sequence in collagen type III for the collagen-binding integrin I domains. Provided herein are the methods used to characterize the sequence, the peptides comprising ...
Cross-reactive displacing antibodies from collagen-binding proteins and method of identification and use
(United States. Patent and Trademark Office, 2007-07-10)
Antibodies to the CNA protein and to other regions from the collagen binding domain, including domain CNA19, are provided, and antibodies produced in this manner have been shown to be cross reactive to both Staphylococcus ...
Prokaryotic collagen-like proteins and uses thereof
(United States. Patent and Trademark Office, 2007-07-03)
The present invention provides recombinant triple helical proteins or collagen-like proteins comprising a prokaryotic protein or one or more domains of a prokaryotic protein comprising a collagen-like peptide sequence of ...
Multicomponent vaccines
(United States. Patent and Trademark Office, 2004-03-09)
Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
Fibronectin binding protein compositions and methods of use
(United States. Patent and Trademark Office, 2006-10-31)
Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...