This dissertation concerns the use of bicyclic guanidinate ligands to prepare new dimetal paddlewheel compounds. Specifically, Ru_2^6+, Re_2^6+, Re_2^7+, and Os_2^7+ compounds will be examined to observe any changes brought ...

Solid-phase syntheses of two 14-membered ring peptidomimetics were done to determine whether or not a beta-turn structure can facilitate macrocyclization. NMR methods, together with CD and QMD calculations, do not fully ...

Two major hallmarks of cancer cells are their ability to sustain proliferative signaling and evade growth suppressors. This can occur when the cell loses transcriptional control of key growth genes through epigenetic ...

Phage display is a widely-used tool for the directed evolution of peptide ligands from large combinatorial peptide libraries. A limitation of this technique arises from the lack of chemical diversity of the phage-displayed ...

The chemical modification of proteins has been a longstanding interest in the scientific community. In addition to the natural modifications necessary for life to function, unnatural covalent modifications are particularly ...

Current academic expectations for evaluation, promotion, and even tenure, have created an environment that places more emphasis on the ability of faculty to demonstrate their impacts on a scholarly level. Although many ...

Emergency Medical Technicians (EMTS) of varying levels of certification have been used to assist in hospital emergency departments since the nursing shortage of the 1980s. Although the literature reflects the controversy ...