dc.creator | Ober, Elizabeth Sally Ward | |
dc.creator | Devanboyina, Venkata Siva Charan | |
dc.creator | Ober, Raimund Johannes | |
dc.date.accessioned | 2023-05-03T13:33:43Z | |
dc.date.available | 2023-05-03T13:33:43Z | |
dc.date.issued | 10/4/2022 | |
dc.identifier.uri | https://hdl.handle.net/1969.1/197564 | |
dc.description.abstract | The present disclosure includes a fusion protein, called a "Seldeg", including a targeting component that specifically binds to a cell surface receptor or other cell surface molecule at near-neutral pH, and an antigen component fused directly or indirectly to the targeting component. The antigen component is configured to specifically bind a target antigen-specific antibody. The present disclosure also includes a method of depleting a target antigen-specific antibody from a patient by administering to the patient a Seldeg having an antigen component configured to specifically bind the target antigen-specific antibody. | en |
dc.language | EN | |
dc.publisher | United States. Patent and Trademark Office | en |
dc.rights | Public Domain (No copyright - United States) | en |
dc.rights.uri | http://rightsstatements.org/vocab/NoC-US/1.0/ | |
dc.title | Fusion Proteins (Seldegs) For Selectively Depleting Antigen-specific Antibodies And Methods Of Use Thereof | en |
dc.type | Utility patent | en |
dc.format.digitalOrigin | reformatted digital | en |
dc.description.country | US | |
dc.contributor.assignee | Texas A&M University System | en |
dc.identifier.patentapplicationnumber | 16/465975 | |
dc.date.filed | 12/1/2017 | |
dc.publisher.digital | Texas A&M University. Libraries | |
dc.subject.cpcprimary | C07K 16/2881 | |
dc.subject.cpcprimary | C07K 14/71 | |
dc.subject.cpcprimary | C07K 2317/77 | |
dc.subject.cpcprimary | C07K 2317/92 | |
dc.subject.cpcprimary | A61K 38/00 | |
dc.subject.cpcprimary | C07K 2319/30 | |
dc.subject.cpcprimary | C07K 2317/71 | |
dc.subject.cpcprimary | C07K 2317/72 | |
dc.subject.cpcprimary | C07K 2317/52 | |
dc.subject.cpcprimary | A61K 51/1027 | |
dc.subject.cpcprimary | C07K 2317/76 | |
dc.subject.cpcprimary | C07K 2317/569 | |