dc.creator | Varanasi, Venu | |
dc.creator | Aswath, Pranesh | |
dc.creator | Maginot, Megen | |
dc.creator | Lavrick, Nickolay V. | |
dc.date.accessioned | 2021-06-02T22:02:02Z | |
dc.date.available | 2021-06-02T22:02:02Z | |
dc.date.issued | 2021-01-26T00:00:00Z | |
dc.identifier.uri | https://hdl.handle.net/1969.1/193356 | |
dc.description.abstract | Amorphous SiOx (SiO2), SiONx, silicon nitride (Si3N4), surface treatments are provided, on both metal (titanium) and non-metal surfaces. Amorphous silicon-film surface treatments are shown to enhance osteoblast and osteoblast progenitor cell bioactivity, including biomineral formation and osteogenic gene panel expression, as well as enhanced surface hydroxyapatite (HA) formation. A mineralized tissue interface is provided using the amorphous silicon-based surface treatments in the presence of osteoblasts, and provides improved bone cell generation/repair and improved interface for secure attachment/bonding to bone. Methods for providing PEVCD-based silicon overlays onto surfaces are provided. Methods of increasing antioxidant enzyme (e.g., superoxide dismutase) expression at a treated surface for enhanced healing are also provided. Continuous generation and release of Si4+ ion into an in vitro or in vivo environment in the presence of osteoblasts/osteoblast progenitor cells, methods of employing same for enhancing the rate of bone healing/bone regeneration, is also described. | en |
dc.language | EN | |
dc.publisher | United States. Patent and Trademark Office | |
dc.rights | Public Domain (No copyright - United States) | en |
dc.rights.uri | http://rightsstatements.org/vocab/NoC-US/1.0/ | |
dc.title | Amorphous silicon oxide, amorphous silicon oxynitride, and amorphous silicon nitride thin films and uses thereof | en |
dc.type | Utility patent | en |
dc.format.digitalOrigin | reformatted digital | en |
dc.description.country | US | |
dc.contributor.assignee | Texas A&M University System | |
dc.contributor.assignee | Board or Regents, University of Texas System | |
dc.contributor.assignee | UT-Battelle, LLC | |
dc.identifier.patentapplicationnumber | 14/848107 | |
dc.date.filed | 2015-09-08T00:00:00Z | |
dc.publisher.digital | Texas A&M University. Libraries | |
dc.subject.cpcprimary | A61L 31/088 | |
dc.subject.cpcprimary | A61L 31/16 | |
dc.subject.cpcprimary | C23C 16/0281 | |
dc.subject.cpcprimary | C23C 16/401 | |
dc.subject.cpcprimary | C23C 16/308 | |
dc.subject.cpcprimary | A61L 2430/02 | |
dc.subject.cpcprimary | A61L 2420/02 | |
dc.subject.cpcprimary | A61L 2300/102 | |
dc.subject.cpcprimary | A61L 2400/18 | |
dc.subject.cpcprimary | A61L 2300/412 | |