dc.creator | Groppe, Jay Clemens | |
dc.date.accessioned | 2019-06-17T17:14:23Z | |
dc.date.available | 2019-06-17T17:14:23Z | |
dc.date.issued | 2018-05-22 | |
dc.identifier.uri | https://hdl.handle.net/1969.1/177249 | |
dc.description.abstract | The claimed invention is directed to a method for screening a compound that binds to an allosteric site of ALK2, the method comprising screening for a compound that is capable of destabilizing the ALK2 protein. A further aspect of the invention is directed to a pharmaceutical composition for the treatment and/or prophylaxis of a disease in a vertebrate, said composition comprising at least one ALK receptor kinase inhibitor, and optionally a pharmaceutically acceptable carrier, adjuvant and/or diluent. | en |
dc.language | eng | |
dc.publisher | United States. Patent and Trademark Office | |
dc.rights | Public Domain (No copyright - United States) | en |
dc.rights.uri | http://rightsstatements.org/vocab/NoC-US/1.0/ | |
dc.title | Inhibitors of activin-like receptor kinases | en |
dc.type | Utility patent | en |
dc.format.digitalOrigin | reformatted digital | en |
dc.description.country | US | |
dc.contributor.assignee | The Texas A & M University System | |
dc.identifier.patentapplicationnumber | 15/003497 | |
dc.date.filed | 2016-01-21 | |
dc.publisher.digital | Texas A&M University. Libraries | |
dc.subject.cpcprimary | A61K 31/496 | |
dc.subject.cpcprimary | A61K 31/4439 | |
dc.subject.cpcprimary | A61K 31/454 | |
dc.subject.cpcprimary | A61K 31/4545 | |
dc.subject.cpcprimary | A61K 31/473 | |
dc.subject.cpcprimary | C12Q 1/485 | |
dc.subject.cpcprimary | G01N 2333/912 | |
dc.subject.cpcprimary | G01N 2500/04 | |
dc.subject.cpcprimary | G01N 2500/20 | |