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    Inhibitors of activin-like receptor kinases

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    9974784.pdf (663.8Kb)
    Date
    2018-05-22
    Author
    Groppe, Jay Clemens
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    Abstract
    The claimed invention is directed to a method for screening a compound that binds to an allosteric site of ALK2, the method comprising screening for a compound that is capable of destabilizing the ALK2 protein. A further aspect of the invention is directed to a pharmaceutical composition for the treatment and/or prophylaxis of a disease in a vertebrate, said composition comprising at least one ALK receptor kinase inhibitor, and optionally a pharmaceutically acceptable carrier, adjuvant and/or diluent.
    URI
    https://hdl.handle.net/1969.1/177249
    Subject
    A61K 31/496
    A61K 31/4439
    A61K 31/454
    A61K 31/4545
    A61K 31/473
    C12Q 1/485
    G01N 2333/912
    G01N 2500/04
    G01N 2500/20
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    • Texas A&M University Patents
    Citation
    Groppe, Jay Clemens (2018). Inhibitors of activin-like receptor kinases. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /177249.

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