Decorin proteoglycan inhibitor of fibrinogen blood clotting

dc.creator	Höök, Magnus
dc.creator	Dugan, Tracey A.
dc.date.accessioned	2019-06-17T17:01:16Z
dc.date.available	2019-06-17T17:01:16Z
dc.date.issued	2006-08-22
dc.identifier.uri	https://hdl.handle.net/1969.1/176826
dc.description.abstract	The present invention provides compositions and methods of inhibiting fibrin(ogen) clot formation by utilizing decorin proteoglycan as an anticoagulating and antithrombotic agent. The decorin proteoglycan comprises a decorin core protein or a fragment thereof covalently linked to a galactosaminoglycan polysaccharide. The decorin core protein acts as an anticoagulant and as a carrier for the delivery of an antithrombotic galactosaminoglycan to fibrinogen. Fibrin clotting is inhibited by the decorin proteoglycan in a concentration-dependent fashion.	en
dc.language	eng
dc.publisher	United States. Patent and Trademark Office
dc.rights	Public Domain (No copyright - United States)	en
dc.rights.uri	http://rightsstatements.org/vocab/NoC-US/1.0/
dc.title	Decorin proteoglycan inhibitor of fibrinogen blood clotting	en
dc.type	Utility patent	en
dc.format.digitalOrigin	reformatted digital	en
dc.description.country	US
dc.contributor.assignee	The Texas A&M University System
dc.identifier.patentapplicationnumber	10/898841
dc.subject.uspcprimary	530/350
dc.date.filed	2004-07-26
dc.publisher.digital	Texas A&M University. Libraries
dc.subject.cpcprimary	A61K 38/1709
dc.subject.cpcprimary	C07K 14/4725
dc.subject.cpcprimary	A61K 47/61
dc.subject.cpcprimary	A61K 38/1709
dc.subject.cpcprimary	A61K 2300/00