dc.creator | Hook, Magnus A. | |
dc.creator | Brown, Eric L. | |
dc.date.accessioned | 2019-06-17T16:57:27Z | |
dc.date.available | 2019-06-17T16:57:27Z | |
dc.date.issued | 2003-02-11 | |
dc.identifier.uri | https://hdl.handle.net/1969.1/176724 | |
dc.description.abstract | Borrelia burgdorferi, the causative agent of Lyme disease, expresses on its surface a decorin binding protein, DbpA and DbpB. Lysine residues necessary for DbpA binding to decorin and DbpA peptides containing these critical residues essential for decorin binding are disclosed. It is further disclosed that vaccination using peptides incorporating these critical binding domains of DbpA can confer a delayed-type hypersensitivity response to DbpA and reduce the number of B. burgdorferi organisms present in infected animals. | en |
dc.language | eng | |
dc.publisher | United States. Patent and Trademark Office | |
dc.rights | Public Domain (No copyright - United States) | en |
dc.rights.uri | http://rightsstatements.org/vocab/NoC-US/1.0/ | |
dc.title | Decorin binding protein essential peptides and methods of use | en |
dc.type | Utility patent | en |
dc.format.digitalOrigin | reformatted digital | en |
dc.description.country | US | |
dc.contributor.assignee | The Texas A&M University System | |
dc.identifier.patentapplicationnumber | 09/596120 | |
dc.subject.uspcprimary | 424/185.1 | |
dc.subject.uspcother | 424/130.1 | |
dc.subject.uspcother | 424/184.1 | |
dc.subject.uspcother | 424/234.1 | |
dc.subject.uspcother | 435/7.2 | |
dc.subject.uspcother | 530/324 | |
dc.date.filed | 2000-06-16 | |
dc.publisher.digital | Texas A&M University. Libraries | |
dc.subject.cpcprimary | C07K 14/20 | |
dc.subject.cpcprimary | Y02A 50/30 | |
dc.subject.cpcprimary | Y02A 50/401 | |
dc.subject.cpcprimary | A61K 39/00 | |