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    Oral immunization with transgenic plants

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    6194560.pdf (2.982Mb)
    Date
    2001-02-27
    Author
    Arntzen, Charles J.
    Mason, Hugh S.
    Haq, Tariq A.
    Metadata
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    Abstract
    The oral vaccines and oral vaccine adjuvants of the present invention are produced in transgenic plants and then administered through the consumption of the transgenic plant. DNA sequences both natural and synthetic encoding for the expression of immunogenic agents which are capable of causing an immune response in animals when fed in edible plants, plant tissues, or derived plant materials are constructed and plants transformed for stable or transient expression in plant cells. The present invention provides the first known functional method for immunizing animals via transgenic plants, where the plants express bacterial antigens that act as both immunogens and adjuvants when the transgenic plant material expressing the antigens is fed to animals.
    URI
    https://hdl.handle.net/1969.1/176658
    Subject
    536/23.7
    424/184.1
    424/185.1
    424/186.1
    424/190.1
    424/192.1
    424/193.1
    424/204.1
    424/227.1
    424/236.1
    424/241.1
    424/282.1
    435/69.1
    435/69.3
    435/252.3
    435/252.33
    435/252.8
    435/320.1
    435/410
    435/419
    530/350
    536/23.1
    800/278
    800/288
    800/295
    C07K 14/245
    C12N 15/8258
    C07K 14/005
    A61P 37/02
    C12N 2770/16022
    A61K 39/00
    Collections
    • Texas A&M University Patents
    Citation
    Arntzen, Charles J.; Mason, Hugh S.; Haq, Tariq A. (2001). Oral immunization with transgenic plants. United States. Patent and Trademark Office; Texas A&M University. Libraries. Available electronically from https : / /hdl .handle .net /1969 .1 /176658.

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