Now showing items 1-10 of 10

    • Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby 

      Hook, Magnus; Xu, Yi; Sillanpaa, Jouko V.; Sthanam, Narayana; Ponnuraj, Karthe; Patti, Joseph M.; Hutchins, Jeff T.; Hall, Andrea; Bowden, Maria G. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2010-12-14)
      A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can ...
    • Decorin binding protein compositions and methods of use 

      Guo, Betty P.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-06-19)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • Decorin binding protein essential peptides and methods of use 

      Hook, Magnus A.; Brown, Eric L. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2003-02-11)
      Borrelia burgdorferi, the causative agent of Lyme disease, expresses on its surface a decorin binding protein, DbpA and DbpB. Lysine residues necessary for DbpA binding to decorin and DbpA peptides containing these critical ...
    • Fibronectin binding protein compositions and methods of use 

      Hook, Magnus; Patti, Joseph M.; House-pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2006-10-31)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
    • Fibronectin binding protein compositions and methods of use 

      Hook,Magnus; Patti, Joseph M.; House-pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-02-03)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
    • MHC II analog from Staphylococcus aureus 

      Hook, Magnus; Jonsson, Klas; Patti, Joseph M.; Gurusiddappa, Sivashankarappa (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 1997-07-15)
      Staphylococcus aureus can bind a number of different extracellular matrix proteins. Recent studies have shown that one particular Staphylococcus protein has the capacity of binding several different matrix proteins. The ...
    • Oral immunization with transgenic plants 

      Arntzen, Charles J.; Mason, Hugh S.; Haq, Tariq A. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2001-02-27)
      The oral vaccines and oral vaccine adjuvants of the present invention are produced in transgenic plants and then administered through the consumption of the transgenic plant. DNA sequences both natural and synthetic encoding ...
    • Staphylococcal immunotherapeutics via donor selection and donor stimulation 

      Patti, Joseph M.; Foster, Timothy J.; Hook, Magnus (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-02-17)
      A method and composition for the passive immunization of patients infected with or susceptible to infection from Staphylococcus bacteria such as S. aureus and S. epidermidis infection is provided that includes the selection ...
    • Surface proteins from gram-positive bacteria having highly conserved motifs and antibodies that recognize them 

      Xu, Yi; Hook, Magnus A. O. (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2004-09-14)
      Isolated peptide sequences and proteins containing these sequences are provided which are useful in the prevention and treatment of infection caused by Gram-positive bacteria. The peptide sequences have been shown to be ...
    • Vaccine vectors and methods of enhancing immune responses 

      Berghman, Luc; Bottje, Walter; Hargis, Billy; Layton, Sherryll (United States. Patent and Trademark OfficeTexas A&M University. Libraries, 2015-02-17)
      Provided herein are vaccine vectors including an antigenic polypeptide and an HMGB1 polypeptide present on the surface of the vaccine vector. Compositions comprising the vaccine vectors are also provided and include a ...