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Now showing items 391-400 of 421
Shape memory polymer scaffolds for tissue defects
(United States. Patent and Trademark Office, 2018-03-27)
A method of making a shape memory polymer (SMP) tissue scaffold includes forming a salt template and adding a macromer solution to the salt template. The macromer solution may include a photoinitiator solution. The method ...
HSP20 inhibits amyloidogenesis and neurotoxicity
(United States. Patent and Trademark Office, 2017-10-31)
The present invention compositions and methods of using at least a portions of an isolated and purified α-crystallin polypeptide that includes one or more β-pleated sheets and that prevents neurotoxicity and amyloidogenesis.
Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases
(United States. Patent and Trademark Office, 2017-08-15)
The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, ...
Designer collagens and use thereof
(United States. Patent and Trademark Office, 2017-08-08)
The present disclosure provides synthetic collagen and methods of making and using synthetic collagen that include a synthetic collagen that facilitates wound closure comprising an isolated and purified triple helical ...
Shape-memory polymer foam device for treating aneurysms
(United States. Patent and Trademark Office, 2017-05-30)
A system for treating an aneurysm in a blood vessel or vein, wherein the aneurysm has a dome, an interior, and a neck. The system includes a shape memory polymer foam in the interior of the aneurysm between the dome and ...
Treatment of gum diseases and gum disorders with TSG-6 protein
(United States. Patent and Trademark Office, 2017-06-13)
A method of treating or preventing a gum disease or gum disorder or gum injury in a mammal by administering to the mammal at least one inflammation modulatory or anti-inflammatory protein or polypeptide, such as TSG-6 ...
Diastolic recoil method and device for treatment of cardiac pathologies
(United States. Patent and Trademark Office, 2017-05-09)
The present invention provides methods and direct cardiac contact device to improve the diastole phase and the systolic phase of a heart and includes a biocompatible film pneumatic locked to the heart to aid in heart ...
Compositions and methods for the delivery of molecules into live cells
(United States. Patent and Trademark Office, 2017-05-30)
The present disclosure provides methods and compositions related to the cytosolic delivery of proteins and cell-impermeable small molecules into live cells using an endosomolytic dimer of cell-penetrating peptide TAT.
Vascular prosthesis for leak prevention during endovascular aneurysm repair
(United States. Patent and Trademark Office, 2019-11-26)
An embodiment includes a process for treating an abdominal aortic aneurysm (AAA) endoleak with a shape memory polymer (SMP) foam device. First, a bifurcated stent graft is placed within the aneurysm while a micro guidewire ...
In vivo live 3D printing of regenerative bone healing scaffolds for rapid fracture healing
(United States. Patent and Trademark Office, 2019-10-15)
Bio-Inks and methods of using compositions comprising the bio-Inks are disclosed. 3-D tissue repair and regeneration through precise and specific formation of biodegradable tissue scaffolds in a tissue site using the ...