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Use of bacterial beta-lactamase for in vitro diagnostics and in vivo imaging, diagnostics and therapeutics
(United States. Patent and Trademark Office, 2016-09-13)
Provided herein are assays and in vitro methods to determine susceptibility to a drug effective against a pathogenic bacteria, for example, a pathogenic Mycobacteria, that has a beta-lactamase activity. An excitation ...
Functional, cross-linked nanostructures for tandem optical imaging and therapy
(United States. Patent and Trademark Office, 2016-03-29)
The present invention provides optical agents comprising optically functional cross linked supramolecular structures and assemblies useful for tandem optical imaging and therapy. Supramolecular structures and assemblies ...