Browsing by Subject "Bioinformatics"
Now showing items 1-18 of 18
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(2020-06-18)Medical diagnosis is the most critical component in the treatment of a patient. But diagnosis often is a complicated process since a myriad of diseases share the same symptoms. If a patient is diagnosed with a disease in ...
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(2012-07-16)Determining which genes are essential for growth of a bacterial organism is an important question to answer as it is useful for the discovery of drugs that inhibit critical biological functions of a pathogen. To evaluate ...
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(2009-05-15)Life sciences research is advancing in breadth and scope, affecting many areas of life including medical care and government policy. The field of Bioinformatics, in particular, is growing very rapidly with the help of ...
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(2012-02-14)We are concerned with testing for differential expression and consider three different aspects of such testing procedures. First, we develop an exact ANOVA type model for discrete gene expression data, produced by ...
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(2020-10-27)Drug resistance is a fundamental barrier to developing robust antimicrobial and anticancer therapies. Its first sign was observed in the 1940s, soon after discovering penicillin, the first modern antibiotic. This dissertation ...
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Comparative Analysis of Error Correction in High-throughput Sequences for the Human Gut Microbiome With the development of high-throughput sequencing tools over the last few decades, the sequencing of genomic data at a large scale at a relatively low cost has drastically revolutionized the field of bioinformatics. ...
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(2021-07-06)The human cell-free DNA (cfDNA) methylation profile in liquid biopsy has been utilized to diagnose early-stage disease and estimate therapy response. However, typical clinical procedures are capable of purifying only very ...
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(2009-05-15)MicroRNAs are a large family of 21-26 nucleotide non-coding RNAs with a role in the post-transcriptional regulation of gene expression. In recent years, microRNAs have been proposed to play a significant role in the expansion ...
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(2018-06-01)Cancer is a disease associated with uncontrolled cell proliferation or reduced cell death, either of which can lead to tumorigenesis. A possible route through which cancer can develop is by breakdowns in the signaling ...
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(2022-11-07)Despite the unique genetic contribution of sex chromosomes, their studies generally lag behind the rest of the genome. Therefore, the aim of this thesis is to advance the assembly, annotation of sex chromosomes in domestic ...
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(2013-08-06)The carboxylate biofuels platform (CBP) involves the conversion of cellulosic biomass into carboxylate salts by a mixed microbial community. Chemical engineering approaches to convert these salts to a variety of fuels ...
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(2012-10-19)Sorghum (Sorghum bicolor [L.] Moench) is the world's fifth most economically important cereal crop, grown worldwide as a source of food for both humans and livestock. Sorghum is a C4 grass that is well adapted to hot and ...
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(2009-05-15)Multiple sequence alignment is an important bioinformatics problem, with applications in diverse types of biological analysis, such as structure prediction, phylogenetic analysis and critical sites identification. In recent ...
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(2018-11-06)Jasmonic Acid (JA) is one of the important substances that associates with stomatal closure under drought stress for maize. In this project, we performed multiple network analyses to identify the expression patterns of JA ...
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(2009-05-15)Bioinformatics resources should provide simple and flexible support for genomics research. A huge amount of gene mapping data, micro-array expression data, expressed sequence tags (EST), BAC sequence data and genome sequence ...
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With the substantial global population growth, it is estimated that the population will be nearing around 9.7 billion by 2050. With this in hand, the demand for food production is an imminent matter in question that must ...
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(2019-10-17)Many different response-pathways enable microorganisms to respond to changes in the environment. Two environmental conditions that elicit responses in the model filamentous fungus Neurospora crassa are light and osmotic ...
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(2009-05-15)Prediction of functions of genes in a genome is a key step in all genome sequencing projects. Sequences that carry out important functions are likely to be conserved between evolutionarily distant species and can be ...