Network Analysis to Reveal Jasmonic Acid Pathway Related Mechanistic Changes for Drought-Tolerant Maize
Abstract
Jasmonic Acid (JA) is one of the important substances that associates with
stomatal closure under drought stress for maize. In this project, we performed multiple
network analyses to identify the expression patterns of JA pathway genes in drought
responses of different maize genotypes where certain genes from the related pathway
were knocked out. Differential gene expression analysis was performed to identify
differentially expressed genes across different water conditions for each maize genotype,
respectively. As the number of samples is limited in this project, we used partial
correlation for co-expression network construction for different genotypes using the
identified DEGs and a weighted LASSO regression method that applies to all samples
for detailed network connectivity analyses of the JA pathway. The results reveal the
changes of behaviors and regulatory relationships of JA pathway genes in different
genotypes. We discussed the shifting of behaviors between different genotypes from the
analysis results.
Citation
Liu, Fan (2018). Network Analysis to Reveal Jasmonic Acid Pathway Related Mechanistic Changes for Drought-Tolerant Maize. Master's thesis, Texas A & M University. Available electronically from https : / /hdl .handle .net /1969 .1 /174499.