Browsing by Author "Zhou, Yubin"
Now showing items 1-20 of 20
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Fakieh, Razan A. (2022-12-12)During C. elegans development, EGF signal from the anchor cell (AC) induces the roughly six equipotent vulval precursor cells (VPCs) to assume the pattern 3˚-3˚-2˚-1˚-2˚-3˚ of cell fates. The VPC closest to the AC is induced ...
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Jing, Ji (2018-05-03)Peroxisomes are single membrane-bound and autonomously replicating subcellular organelles. While their function as metabolic organelles is well known, their place in the world of cell signaling is only just beginning to ...
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Liu, Yang (2019-04-18)Membrane proteins interact intimately with the lipid bilayer in which they are embedded. Interactions between membrane proteins and ligands such as lipids and other small molecules can affect protein structure and function. ...
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Kang, Mingsong (2014-08-28)The complement system, a major component of the innate immunity, is critical for combating microbial infections. It can be activated by three distinct pathways: the classical pathway, the lectin pathway and the alternative ...
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Lee, Minjung (2020-07-09)Immunotherapy is one of the fastest growing fields in cancer research and treatment. It largely relies on the immune system and is impacted by tumor infiltrated immune cells, which perform an important function in the tumor ...
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Tan, Peng (2018-05-07)The innate immune system has the ability to tune the inflammatory environment by modulating pathogen-recognition receptors (PRRs) signaling, which can either induce oncogenic changes or generate antitumor immunity through ...
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Ke, Yuepeng (2022-04-19)Prostate cancer (PCa) is the third leading cause of cancer death. The lack of an effective cure for advanced stages and an overall low response to immunotherapy give prominence to the critical need for developing novel ...
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He, Lian (2018-05-03)Calcium (Ca^2+) acts as a universal second messenger to regulate a myriad of biological processes, including gene expression, cell metabolism, lymphocyte activation and cell growth. In non-excitable cells such as cells of ...
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Liang, Yi (2017-12-12)The conversion of 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and further oxidized species is catalyzed by the Ten-eleven translocation (TET) methylcytosine dioxygenase. Here we provided a temporal control ...
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Powell, Reid Trenton (2018-07-16)High throughput drug screening has greatly progressed drug discovery for diseases such as cancer. Specifically, the introduction of the automated microscope in high throughput drug screening has facilitated the acquisition ...
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Yin, Chunhui (2019-06-24)Background: Myotoxins are a family of small protein toxins present in the venom of multiple species of pit vipers that have selective toxic effects on different types of tissues. Method: In order to better protect people ...
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Ma, Guolin; Wei, Ming; He, Lian; Liu, Chongxu; Wu, Bo; Zhang, Shenyuan; Jing, Ji; Liang, Xiaowen; Senes, Alessandro; Tan, Peng; Li, Siwei; Sun, Aomin; Bi, Yunchen; Zhong, Ling; Si, Hongjiang; Shen, Yuequan; Li, Minyong; Lee, Mi-Sun; Zhou, Weibin; Wang, Junfeng; Wang, Youjun; Zhou, Yubin (Nature Communications, 2015)
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Yang, Tingli (2017-12-14)High-fat diet (HFD)-induced obesity is a risk factor contributing to cardiovascular disease. Excessive accumulation of fatty acids in the heart can cause cardiac dysfunction and heart failure and is referred to as lipotoxic ...
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Zhou, Yubin; Huang, Yun; Nguyen, Nhung T.; He, Lian (United States. Patent and Trademark Office; Texas A&M University. Libraries, 8/23/2022)In an embodiment, a device for modulating intracellular gene expression, the device having a calcium actuator component and a transcription reprogramming component. In another embodiment, a method for modulating intracellular ...
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He, Lian; Zhang, Yuanwei; Ma, Guolin; Tan, Peng; Li, Zhanjun; Zang, Shengbing; Wu, Xiang; Jing, Ji; Fang, Shaohai; Zhou, Lijuan; Wang, Youjun; Huang, Yun; Hogan, Patrick G; Han, Gang; Zhou, Yubin; Aldrich, Richard (ELife, 2015)
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Shin, Hanna (2018-11-07)An EGF gradient induces the equipotent C. elegans vulval precursor cells (VPCs) to assume the 3˚-3˚-2˚-1˚-2˚-3˚ pattern of cell fates. EGF triggers the LET-60/Ras-LIN-45/Raf-MEK-2/MEK-MPK-1/ERK canonical MAP kinase cascade ...
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Dai, Yuan (2018-02-20)Cardiac inflammatory response after myocardial infarction (MI) is essential to clear necrotic myocardium for cardiac healing, while excessive and prolonged inflammation extends the infarction and promotes adverse cardiac ...
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Nguyen, Nhung Thi Thi (2020-12-01)Synthetic biology is an interdisciplinary field of science that involves the redesign and fabrication of biological components to synthesize a modified and advanced biological system to solve problems in medicine, agriculture, ...
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Quintana, Ariel; Rajanikanth, Vangipurapu; Farber-Katz, Suzette; Gudlur, Aparna; Zhang, Chen; Jing, Ji; Zhou, Yubin; Rao, Anjana; Hogan, Patrick (Proceedings of the National Academy of Sciences of the United States of America, 2015)
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Zhang, Yifan (2016-11-30)Toll-like receptors (TLRs) are pattern recognition receptors (PRRs) that recognize pathogen-associated molecular patterns (PAMPs). The recognition leads to the activation of TLR signaling pathway, which initiates innate ...