Browsing by Author "Sorg, Joseph"
Now showing items 1-18 of 18
-
Meyers, William MatthewEndospore formation by Clostridium difficile is a vital part of the life cycle for this Gram-positive bacterium. During this process, the mothercell packages proteins into the developing endospore. However, the mechanisms ...
-
Mai, Diana (2017-04-24)Clostridium difficile is an antibiotic-resistant Gram-positive bacterium. It has become a major concern for hospitals and acute care medical wards where antibiotics are used more readily. Therapies and preventative measures ...
-
Francis, Michael (2017-05-10)Infections caused by Clostridium difficile have increased steadily over the past several years. While studies on C. difficile virulence and physiology have been hindered, in the past, by lack of genetic approaches and ...
-
Ravichandran, Akshaya (2016-12-08)Fungal infections caused by opportunistic pathogens tend to be particularly severe and systemic in the case of immunocompromised patients. The current treatment options fall under classes such as azoles, polyenes, echinocandins ...
-
Talmage, Sara Jean (2019-08-06)The nucleus is the brain of the cell and is the site of regulation of processes such as DNA replication, transcription and cell cycle. Given its importance in cell function, several known bacterial proteins have been shown ...
-
Cothrell, Andrew T (2021-04-27)Fungal infections caused by opportunistic pathogens can be severe and have been growing in prevalence. Many clinically relevant pathogens have resistance to or are developing a resistance to the commonly used treatments. ...
-
Francis, Michael; Sorg, Joseph (MSphere, 2016)
-
Girinathan, Brintha; Monot, Marc; Boyle, Daniel; McAllister, Kathleen; Sorg, Joseph; Dupuy, Bruno; Govind, Revathi (MSphere, 2017)
-
Bouillaut, Laurent; McBride, Shonna; Sorg, Joseph; Schmidt, Diane; José M. Suarez; Tzipori, Saul; Mascio, Carmela; Chesnel, Laurent; A. L. Sonenshein (Antimicrobial Agents and Chemotherapy, 2015)
-
Zhang, Chengxi (2020-07-30)In natural habitats, microorganisms synthesize specialized metabolites and enzymes that mediate chemical interactions between organisms. Those natural products have various biological activities, acting as signaling ...
-
Bhattacharjee, Disha; McAllister, Kathleen; Sorg, Joseph (Journal of Bacteriology, 2016)
-
Escano, Jerome (2016-12-08)The rise of antibiotic-resistant bacteria poses a large problem for healthcare systems across the world. This problem is further exacerbated by the lack of development in new types of antibiotics. The CDC has identified ...
-
Lai Hing, Steven Kenneth (2017-12-07)Natural products have long been a template by which science has produced medicines which have saved millions of lives. Bacterial sources have yielded many peptide based drugs which continue to show great value against ...
-
Bhattacharjee, Disha; Francis, Michael; Ding, Xicheng; McAllister, Kathleen; Shrestha, Ritu; Sorg, Joseph (Journal of Bacteriology, 2016)
-
Francis, Michael; Allen, Charlotte; Sorg, Joseph (Journal of Bacteriology, 2015)
-
Williams, McKinley Donovan (2020-04-16)Antimicrobial resistance is a wide-reaching concern, having garnished increased saliency amongst all corners of society. These fears are well founded and attempts to moderate and effectively respond to this potential crisis ...
-
Caraway, Emma Britain (2016-08-23)Microbial extremophiles have the potential for a wide variety of biotechnological and industrial applications and yet extremophiles are underrepresented in whole genome sequencing efforts to date. The generation of whole ...
-
Gyawali, Rachana (2016-12-09)Sexual reproduction is conserved and maintained in all major eukaryotic lineages. The fungus Cryptococcus neoformans is known to undergo a-α bisexual mating and also unisexual mating, with bisexual mating being far more ...