Browsing by Author "Massett, Michael"
Now showing items 1-11 of 11
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Macias, Brandon 1979- (2012-10-25)Human exposure to reduced weightbearing results in bone loss. The rate of bone loss during microgravity exposure is similar to that of a post-menopausal women. In fact, the maintenance of bone mass is intimately dependent ...
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Little, Sarah Elizabeth (2020-04-27)Chronic inflammation leads to bone loss and fragility. Signaling of proinflammatory cytokines, like tumor necrosis factor-alpha (TNFα), is integral to promote bone resorption. Dietary modulation of pro-inflammatory cytokines ...
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Shin, Song Yi (2022-11-17)Vasoconstrictor function, which is essential for vascular homeostasis, declines with aging. Aging induces molecular alterations, leading to the gradual loss of vascular homeostasis. Thus, aging is a significant risk factor ...
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Luttrell, Meredith Joy (2014-04-14)Endothelial dysfunction is a major risk factor for the development of cardiovascular diseases, and aging is associated with a gradual decline in endothelial function. Furthermore, endothelial dysfunction in arteries and ...
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Letsinger, Ayland Cash (2019-07-25)Physical activity is a well-established preventative for many diseases, yet the average United States citizen does not engage in regular exercise. Thus, there is a need to understand the biological and environmental ...
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Seung Kyum Kim; Massett, Michael (Frontiers in Physiology, 2016)
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Seawright, John Weston (2016-01-08)Peripheral arterial function is impaired with age, increasing the risk of cardiovascular disease. One therapeutic modality for improving arterial function in aged arteries is aerobic exercise; however, the signals associated ...
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Deaver, John William (2020-09-11)One of the main hubs of cellular metabolic integration is the mechanistic target of rapamycin, or mTOR. In normal, healthy cells, mTOR helps to regulate and balance cellular growth and proliferation against metabolic ...
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Trott, Daniel Wayne (2012-02-14)Aging is associated impaired endothelial function in the skeletal muscle vasculature which contributes to decreased ability to increase muscle blow during exercise. This endothelial dysfunction is mediated, primarily, by ...
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Skeletal Impacts of Continuous Low-Dose-Rate Gamma Radiation Exposure During Simulated Microgravity Bokhari, Rihana (2018-07-03)One of the greatest unknowns in human spaceflight is the effects of low-dose-rate galactic cosmic radiation (GCR). The majority of radiation studies deliver the total radiation dose expected on a 2-3 year mission in minutes. ...
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Ferguson, David Paul (2013-07-01)Physical activity can prevent cardiovascular disease, obesity, type II diabetes and some types of cancer. With only 3.5% of adults meeting the recommended physical activity guidelines, research has focused on the regulatory ...