Browsing by Author "Grau, James W."
Now showing items 1-20 of 30
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Woller, Sarah Ann (2012-07-16)Up to 65% of individuals with a spinal cord injury (SCI) experience neuropathic pain, and cite this as one of the most significant consequences of injury. Opiate analgesics are one of the most effective, but also most ...
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Ferguson, Adam R.; Huie, J. Russell; Crown, Eric D.; Grau, James W. (Frontiers in Physiology, 2012)
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Hoy, Kevin (2012-10-19)Previous research has demonstrated that the spinal cord is capable of a simple form of instrumental learning. In this instrumental learning paradigm, rats typically receive a complete spinal transection at the second ...
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Simon, Nicholas Wayne (2011-08-08)Excessive risk-taking is a characteristic of several psychopathological disorders. In order to alleviate maladaptive risky behavior, a thorough understanding of the neurobiological and pharmacological substrates of risky ...
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Grover, Cathy Ann (Texas A&M University. Libraries, 1992)Forty adult male rats received one of the following diet (25 g/day) and weekly gastric intubation (2 ml) treatments over a 70 day period: Group Con--control diet and 10 intubations of distilled water; Group CPb--lead diet ...
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Illich, Paul Anthony (Texas A&M University. Libraries, 1993)Prior research has shown that an aversive event can produce either an increase (hyperalgesia) or a decrease in pain reactivity (hypoalgesia). Researchers have extensively examined both the behavioral and neurobiological ...
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Prentice, Thomas W. (1993)In this research, it was attempted to elicit the phenomenon of spinally activated antinociception. Surprisingly, the effect failed to be observed. We then attempted to determine whether the effect was due to a difference ...
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Grimes, Jeffrey Scott (Texas A&M University, 2004-09-30)In searching for new human pain models that more closely resemble clinical pain states, the capsaicin pain model has emerged as a viable model for both inflammatory and neuropathic pain states. A principal benefit of the ...
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You, Dokyoung Sophia (2012-10-19)Adverse childhood events have been identified as a risk factor for developing chronic pain conditions in adulthood. However, previous studies have inconsistently supported the link between adverse childhood events and ...
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McLemore, Sherilyn (1998)Prior exposure to shock lowers vocalization thresholds to heat and facilitates the acquisition of conditioned fear when training is conducted in a different context. These observations have been taken as evidence that shock ...
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McKenney, Jesse (1993)Previous research has shown that exposure to inescapable shock produces a hormonally mediated opioid hypoalgesia in rats. In addition, it has a long-term sensitization effect on the opioid system that increases reactivity ...
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Vichaya, Elisabeth Good (2009-05-15)Although neural plasticity has traditionally been studied within the brain, evidence indicates that the spinal cord is quite plastic as well. Spinal neurons can even support a simple form of instrumental learning (Grau et ...
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Vichaya, Elisabeth Good (2012-07-16)A growing body of evidence suggests that social stress contributes to the pathogenesis of neurodegenerative diseases, such as multiple sclerosis (MS). For example, prior research has shown that ...
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Ferguson, Adam R.; Huie, J. Russell; Crown, Eric D.; Baumbauer, Kyle M.; Hook, Michelle A.; Garraway, Sandra M.; Lee, Kuan H.; Hoy, Kevin C.; Grau, James W. (Frontiers in Physiology, 2012)
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Grimes, Jeffrey Scott (Texas A&M University, 2006-10-30)Animal research has elucidated the neurobiological substrates and environmental determinants of pain modulation. Despite these advances, relatively little is known about how psychological processes activate pain modulatory ...
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Grau, James W.; Huie, J. Russell; Lee, Kuan H.; Hoy, Kevin C.; Huang, Yung-Jen; Turtle, Joel D.; Strain, Misty M.; Baumbauer, Kyle M.; Miranda, Rajesh M.; Hook, Michelle A.; Ferguson, Adam R.; Garraway, Sandra M. (Frontiers in Neural Circuits, 2014)
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Chen, Ping-Sun (Kevin) (1991)We have previously shown that exposure to three brief (2 sec) 3.0 mA shocks elicits an opioid hypoalgesia, and that exposure to longer (75 sec) tailshocks elicits a nonopioid hypoalgesia in spinalized rats. The present ...
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Ferguson, Adam Richard (Texas A&M University, 2004-09-30)Prior work from our laboratory has shown that the spinal cord is capable of supporting a simple form of instrumental (response-outcome) learning. In a typical experiment, animals are given a spinal transection at the second ...
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Puga, Denise Alejandra (2009-05-15)A substantial body of work exists to suggest that brain and spinal mechanisms react differently to nociceptive information. The current experiments were design to identify parallels and differences in the way the spinal ...
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Puga, Denise Alejandra (2012-07-16)We utilize a simple instrumental (response-outcome) learning task to measure spinal plasticity in the isolated spinal cord. Peripheral uncontrollable nociceptive input has been shown to disrupt spinal instrumental learning ...