An investigation of receiver probe development for magnetic resonance microscopy

Abstract

Much research in Magnetic Resonance Imaging has been directed toward the development of new hardware systems that can obtain high resolution images, typically on the order of tens of microns, for small field-of-views, typically less than I cm. The objective of the research presented in this thesis is to extend the analysis and design of conventional RF coil systems to that for MR microscopy. Specifically, distinctions in terms of signal and noise are made between conventional RF coils and coils operating in a microscopic environment. Coupling mechanisms are discussed, and methods for achieving maximum SNR are covered. A fully automated PC based measurement system is developed for experimentally characterizing those parameters of interest in the development of coil systems and verifying theoretical results. Design guidelines are established from which coil geometries can be derived that maximize SNR, as well as minimize inductive coupling between elements in a microcoil array. Finally, prototype planar microcoils and microcoil array designs are given that can be rearranged using integrated circuit and printed circuit board fabrication techniques.