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Investigations into the hemodynamic and metabolic effects of fructose 1,6 diphosphate and prostacyclin in hypovolemic shock
| dc.contributor.advisor | Clark, D. R. | |
| dc.contributor.advisor | Jenkins, W. L. | |
| dc.creator | Bland-van den Berg, Paul | |
| dc.date.accessioned | 2020-08-21T21:34:39Z | |
| dc.date.available | 2020-08-21T21:34:39Z | |
| dc.date.issued | 1982 | |
| dc.identifier.uri | https://hdl.handle.net/1969.1/DISSERTATIONS-385276 | |
| dc.description | Typescript (photocopy). | en |
| dc.description.abstract | A modified Wiggers canine hemorrhagic shock model was developed to evaluate the hypotheses that (1) irreversible shock is the result of depletion of tissue ATP levels below a critical point, following which failure of subcellular organelles, cell death, multisystem organ failure and death of the organism occur; (2) fructose 1,6 diphosphate (F1,6 DP) can increase tissue production of ATP by stimulating anaerobiosis; (3) prostacyclin (PGI(,2)) can increase tissue production of ATP by promoting aerobic metabolism through improved tissue blood flow and maintenance of subcellular compartmentalization; (4) the effects of F1,6DP and PGI(,2) may be additive or synergistic. ... | en |
| dc.format.extent | xv, 163 leaves | en |
| dc.format.medium | electronic | en |
| dc.format.mimetype | application/pdf | |
| dc.language.iso | eng | |
| dc.rights | This thesis was part of a retrospective digitization project authorized by the Texas A&M University Libraries. Copyright remains vested with the author(s). It is the user's responsibility to secure permission from the copyright holder(s) for re-use of the work beyond the provision of Fair Use. | en |
| dc.rights.uri | http://rightsstatements.org/vocab/InC/1.0/ | |
| dc.subject | Veterinary Physiology | en |
| dc.subject.classification | 1982 Dissertation B493 | |
| dc.subject.lcsh | Shock | en |
| dc.subject.lcsh | Fructose | en |
| dc.subject.lcsh | Prostacyclin | en |
| dc.subject.lcsh | Nucleotides | en |
| dc.subject.lcsh | Metabolism | en |
| dc.title | Investigations into the hemodynamic and metabolic effects of fructose 1,6 diphosphate and prostacyclin in hypovolemic shock | en |
| dc.type | Thesis | en |
| thesis.degree.discipline | Philosophy | en |
| thesis.degree.grantor | Texas A&M University | en |
| thesis.degree.name | Doctor of Philosophy | en |
| thesis.degree.name | Ph. D. in Philosophy | en |
| thesis.degree.level | Doctorial | en |
| dc.contributor.committeeMember | Green, R. A. | |
| dc.contributor.committeeMember | Hightower, D. F. | |
| dc.type.genre | dissertations | en |
| dc.type.material | text | en |
| dc.format.digitalOrigin | reformatted digital | en |
| dc.publisher.digital | Texas A&M University. Libraries | |
| dc.identifier.oclc | 10039552 |
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