The Appearance Of Alterred Protein Products In Mutagenized Vesicular Stomatitis Virus
Abstract
Mutants of vesicular stomatitis virus (VSV) were generated by treatment during the virus' infective phase with the known frameshift mutagen ICR-191. Both mutant and wild-type viral proteins were labelled with ³⁵ S-methionine, extracted, and examined by SDS-polyacrylamide gel electrophoresis (SDS-PAGE), looking for mutant proteins that exhibited differing mobilities from their corresponding wild-type protein. Two alterred protein products were observed. One involved the G protein while the other involved either the N or NS proteins.
Description
Program year: 1981/1982Digitized from print original stored in HDR
Subject
vesicular stomatitis virusframeshift mutagen ICR-191
wild-type protein
mobilities
G protein
N protein
NS protein
Citation
Brophey, Mike (1982). The Appearance Of Alterred Protein Products In Mutagenized Vesicular Stomatitis Virus. University Undergraduate Fellow. Available electronically from https : / /hdl .handle .net /1969 .1 /CAPSTONE -UriegasR _1979.
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