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G Protein-coupled Estrogen receptor is activated by G-1 which induces a signaling cascade that inhibits breast cancer cell proliferation
(2012-06-08)
Breast cancer is the most common cancer in women and is predominantly estrogen dependent [1]. About 1 in 8 women in the United States (12%) will develop invasive breast cancer over the course of her lifetime. Failure in ...
Identification of Smooth Muscle Gamma Actin in Prostate Epithelia
(2013-09-25)
Prostate cancer is the second most common form of cancer in American men. Though broad treatments are available, these often have deleterious effects on the patient. One approach which may result in a more tailored treatment ...
CHALONE SIGNAL TRANSDUCTION PATHWAY IN DICTYOSTELIUM DISCOIDEUM: A POSSIBLE SIGNALING MECHANISM FOR CELL PROLIFERATION INHIBITION
(2014-10-14)
Cancer is a group of diseases characterized by uncontrolled cell proliferation. Cancer is responsible for nearly 1 of every 4 deaths, and ranks as the second highest cause of death worldwide, and costs the American population ...
GENETIC ANALYSYS OF THE IN VIVO FUNCTION AND REGULATION OF THE ONCOPROTEIN CDK8 IN DROSOPHILA
(2012-05-09)
Cyclin-Dependent Kinase 8 (CDK8) has recently emerged as an oncoprotein that is amplified in both colorectal and melanoma cancers. The importance of CDK8 and its regulatory partner Cyclin C (CycC) is highlighted by the ...