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Search For Regulatory Logic In De Novo Pyrimidine Biosynthesis In Bacteria
(1985)
The de novo pyrimidine biosynthetic pathway produces the pyrimidine end products uridine-5'-triphosphate (UTP) and cytidine-5’-triphosphate (CTP), which lead to the synthesis of new DNA and RNA for cell growth. Aspartate ...
Developmental Regulation of Pyrimidine Biosynthesis in Dictyostelium discoideum
(1982)
The research reported in this thesis demonstrates that the initial steps for pyrimidine biosynthesis in the cellular slime mold Dictyostelium discoideum are catalyzed by the enzymes carbamoyl phosphate synthetase (CPSase, ...
The Production And Characterization Of Monoclonal Antibodies To Aspartate Transcarbamoylase From Escherichia Coli
(1985)
This research project focused on the production of monoclonal antibodies to the holoenzyme aspartate transcarbamoylase (ATCase) and to its component catalytic and regulatory subunits. The hybridoma cell lines were prepared ...
Genetic Manipulation of Aspartate Transcarbamylases from Escherichia coli and Serratia Marcescens
(1983)
Aspartate transcarbamylase (ATCase, EC 2.1.3.2) allosterically modulates de novo pyrimidine biosynthesis in the enteric bacteria. This modulation differs in Escherichia coli and Serratia marcescens, with CTP allosterically ...