dc.creator | Gaharwar, Akhilesh K. | |
dc.creator | Carrow, James K. | |
dc.date.accessioned | 2021-06-02T22:02:03Z | |
dc.date.available | 2021-06-02T22:02:03Z | |
dc.date.issued | 2021-01-26T00:00:00Z | |
dc.identifier.uri | https://hdl.handle.net/1969.1/193357 | |
dc.description.abstract | Aspects of the invention are directed to mineral-based nanoparticles comprising silicate nanoparticles that induce human mesenchymal stem cells (hMSCs) into a cartilage-lineage through the upregulation of cartilage-specific genes resulting in the transformation of the cell phenotype into that of a chondrocyte, i.e., a cartilage producing cell. The silicate nanoparticles are synthesized through a process where the precipitate of sodium silicate is mixed with one or more elements and compounds and milled into nanoparticles. | en |
dc.language | EN | |
dc.publisher | United States. Patent and Trademark Office | |
dc.rights | Public Domain (No copyright - United States) | en |
dc.rights.uri | http://rightsstatements.org/vocab/NoC-US/1.0/ | |
dc.title | Mineral-based nanoparticles for arthritis treatment | en |
dc.type | Utility patent | en |
dc.format.digitalOrigin | reformatted digital | en |
dc.description.country | US | |
dc.contributor.assignee | Texas A&M University System | |
dc.identifier.patentapplicationnumber | 16/060273 | |
dc.date.filed | 2016-12-21T00:00:00Z | |
dc.publisher.digital | Texas A&M University. Libraries | |
dc.subject.cpcprimary | A61K 35/28 | |
dc.subject.cpcprimary | A61K 9/5115 | |
dc.subject.cpcprimary | A61K 35/32 | |
dc.subject.cpcprimary | C08K 3/34 | |
dc.subject.cpcprimary | A61K 9/0024 | |
dc.subject.cpcprimary | A61K 9/5161 | |
dc.subject.cpcprimary | C12N 5/0655 | |
dc.subject.cpcprimary | A61K 9/14 | |
dc.subject.cpcprimary | A61K 47/6923 | |
dc.subject.cpcprimary | B82Y 5/00 | |
dc.subject.cpcprimary | C12N 2533/10 | |
dc.subject.cpcprimary | C12N 2506/1353 | |
dc.subject.cpcprimary | C12N 2500/05 | |
dc.subject.cpcprimary | C08K 2201/011 | |
dc.subject.cpcprimary | B82Y 40/00 | |