Variants of phosphotriesterase for the hydrolysis and detoxification of nerve agents

dc.creator	Raushel, Frank M.
dc.creator	Bigley, Andrew N.
dc.date.accessioned	2019-06-17T17:16:07Z
dc.date.available	2019-06-17T17:16:07Z
dc.date.issued	2019-05-28
dc.identifier.uri	https://hdl.handle.net/1969.1/177296
dc.description.abstract	Variants of phosphotriesterase have been created that exhibit enhanced hydrolysis of V-type and G-type nerve agents over wild-type phosphotriesterase. V- and G-type nerve agents have an SP and RP enantiomer. The SP enantiomers are more toxic. V-type nerve agents are among the most toxic substances known. Variants of phosphotriesterase can prefer to hydrolyze one enantiomer of VX over the other enantiomer.	en
dc.language	eng
dc.publisher	United States. Patent and Trademark Office
dc.rights	Public Domain (No copyright - United States)	en
dc.rights.uri	http://rightsstatements.org/vocab/NoC-US/1.0/
dc.title	Variants of phosphotriesterase for the hydrolysis and detoxification of nerve agents	en
dc.type	Utility patent	en
dc.format.digitalOrigin	reformatted digital	en
dc.description.country	US
dc.contributor.assignee	The Texas A&M University System
dc.identifier.patentapplicationnumber	15/320490
dc.date.filed	2015-06-19
dc.publisher.digital	Texas A&M University. Libraries
dc.subject.cpcprimary	C12N 9/16
dc.subject.cpcprimary	A62D 3/02
dc.subject.cpcprimary	C12Y 301/03008
dc.subject.cpcprimary	C12Y 301/08001
dc.subject.cpcprimary	A62D 2101/02
dc.subject.cpcprimary	A62D 2101/26