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dc.contributor.advisorLeibowitz, Julian
dc.creatorMasud, Faryal 1989-
dc.date.accessioned2013-06-04T16:10:51Z
dc.date.available2013-06-04T16:10:51Z
dc.date.created2011-05
dc.date.issued2011-04-18
dc.date.submittedMay 2011
dc.identifier.urihttps://hdl.handle.net/1969.1/ETD-TAMU-2011-05-9580
dc.identifier.urihttps://hdl.handle.net/1969.1/148765
dc.description.abstractSoftware called SHAPE finder was used to analyze the secondary structure 5’ UTR of MHV. This study was the first time this software has been used for MHV, and if the previous procedures are followed, we will have high resolution results of the RNA secondary structures. Currently, the replication and pathogenesis of MHV is incompletely understood in part because of a lack of an accurate determination of its RNA secondary structure. This will help us better understand its course of proliferation. Since MHV is a good model for other coronaviruses and structures important for replication are most often conserved amongst closely related viruses, this information may provide a better understanding of the replication of related coronaviruses such as SARS-coronavirus.en
dc.format.mimetypeapplication/pdf
dc.subjectmouse, hepatitis, virus, MHV, SHAPE, 5'UTRen
dc.titleSHAPE Analysis of 5’ Untranslated Region of Mouse Hepatitis Virusen
dc.typeThesisen
thesis.degree.departmentBiochemistry and Biophysicsen
thesis.degree.disciplineBiochemistryen
thesis.degree.grantorHonors and Undergraduate Researchen
thesis.degree.nameBachelor of Scienceen
dc.type.materialtexten
dc.date.updated2013-06-04T16:10:51Z


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