Browsing by Author "Mwangi, Waithaka"
Now showing items 1-20 of 34
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Adenovirus-vectored novel African Swine Fever Virus antigens elicit robust immune responses in swine Lokhandwala, Shehnaz; Waghela, Suryakant; Bray, Jocelyn; Sangewar, Neha; Charendoff, Chloe; Martin, Cameron; Hassan, Wisam; Koynarski, Tsvetoslav; Gabbert, Lindsay; Burrage, Thomas; Brake, David; Neilan, John; Mwangi, Waithaka (PloS One, 2017)
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Rocha, Joana Nunes (2018-11-21)Rhodococcus equi is a facultative intracellular pathogen that causes pyogranulomatous pneumonia in foals <6 months of age. Why foals are highly susceptible to R. equi is unknown. R. equi pneumonia is a leading cause of ...
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Carroll, Juliette E. (2011-02-22)Babesiosis is caused by a genus of tick-transmitted apicomplexan parasites with considerable economic, medical, and veterinary impact. Bovine babesiosis is an important impediment to livestock production throughout the ...
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Chou, Wen-Ko (2013-11-26)The best way to prevent infectious disease is to directly establish mucosal immunity and also induce circulatory immunity to avoid pathogen invasion and spread. In our first study, we tested the hypothesis that a single ...
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Martin, Cameron Lee (2017-05-10)Lack of safe and effective adjuvants is a major hindrance to the development of efficacious vaccines. Signaling via CD40 pathway leads to enhanced antigen processing and presentation, nitric oxide expression, pro-inflammatory ...
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Mirhosseini, Negin (2009-05-15)Equine infectious anemia virus (EIAV) is a macrophage-tropic retrovirus that causes persistent disease in horses and ponies. In addition to its structural proteins, EIAV encodes four regulatory/accessory genes, tat, rev, ...
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Brock, Christina Marie (2017-07-28)Lyme disease (LD) is the most prevalent arthropod borne illness in the US. Currently, there is no vaccine to prevent infection with LD in humans, rather, prevention of this disease relies on avoiding exposure to the tick ...
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Lokhandwala, Shehnaz Taher (2017-02-17)The objective of this work was to develop adenovirus-vectored prototype vaccines against two pathogens, African Swine Fever Virus (ASFV) and Bovine Viral Diarrhea Virus (BVDV), which cause disease in two major livestock ...
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Rajput, Mrigendra KS; Darweesh, Mahmoud F; Park, Kaci; Braun, Lyle J; Mwangi, Waithaka; Young, Alan J; Chase, Christopher CL (Virology Journal, 2014)
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Ramirez Carvajal, Lisbeth (2014-07-08)During viral infection, host cell elicits the innate immune response by sensing pathogen associated molecular patterns (PAMPs) and triggering pathways that usually converge in the activation of interferon (IFN) and interferon ...
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Deblois, Kimberley Michelle (2013-02-04)Swine and wild boars in Africa, and parts of Europe and Russia continue being decimated by a severe form of hemorrhagic fever known as African Swine Fever (ASF). This viral disease has been responsible for the deaths of ...
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Pohlenz Castillo, Camilo (2012-02-14)Rapid expansion of the aquaculture industry in recent decades has resulted in infectious diseases emerging as a major constraint to fish production, causing large economical losses worldwide. Therefore, prevention practices ...
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Arenas Gamboa, Angela Maria (2009-05-15)Brucellosis is an important zoonotic disease of nearly worldwide distribution. Despite the availability of live vaccine strains for bovine (S19, RB51) and small ruminants (Rev 1), these vaccines have several drawbacks ...
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Lin, Huaiying 1986- (2013-01-07)Babesia bovis is a causative agent of bovine babesiosis and is transmitted by vector ticks, Rhipicephalus (Boophilus) spp. The disease has a high mortality rate in susceptible cattle, causing serious economic loss. At ...
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Liao, Yifei (2021-03-02)Marek’s disease (MD) is a neoplastic disease of chickens caused by Marek’s disease virus (MDV), a member of the Alphaherpesviridae subfamily. Three MDV serotypes, including MDV-1, MDV-2 and HVT, have been identified and ...
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Gomez, Gabriel (2013-02-26)Despite being amongst the most common zoonotic diseases in the world, brucellosis is a neglected disease for which an approved vaccine for human use does not exist. Thus far, the traditional approaches to Brucella antigen ...
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Immunization with a Borrelia burgdorferi BB0172-Derived Peptide Protects Mice against Lyme Disease Small, Christina M.; Ajithdoss, Dharani K.; Hoffmann, Aline Rodrigues; Mwangi, Waithaka; Esteve-Gassent, Maria D. (PLOS ONE, 2014-02-05)Lyme disease is the most prevalent arthropod borne disease in the US and it is caused by the bacterial spirochete Borrelia burgdorferi (Bb), which is acquired through the bite of an infected Ixodes tick. Vaccine development ...
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Gomez, Gabriel; Pei, Jianwu; Mwangi, Waithaka; Adams, L. Garry; Rice-Ficht, Allison; Ficht, Thomas A.; Bansal, Geetha P. (PloS One, 2013)
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Bordin, Angela Ilha (2014-05-03)Rhodococcus equi is a bacterium commonly isolated from soil that primarily causes pneumonia in foals and immunocompromised adult horses. Many vaccines were designed and tested to protect foals from developing pneumonia; ...
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Bordin, Angela I.; Pillai, Suresh D.; Brake, Courtney; Bagley, Kaytee B.; Bourquin, Jessica R.; Coleman, Michelle; Oliveira, Fabiano N.; Mwangi, Waithaka; McMurray, David N.; Love, Charles C.; Felippe, Maria Julia B.; Cohen, Noah D.; Roop, Roy Martin (PloS One, 2014)