Browsing by Author "Jayaraman, Arul"
Now showing items 1-20 of 125
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Singla, Akshi (2020-04-17)Bacterial resistance is rapidly emerging worldwide, endangering the efficacy of existing antibiotics. As a result, extensive research is being done on the development of new antimicrobials; however, these new drugs could ...
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A Microfluidic Model to Study Host-Microbiota Interactions in the Colorectal Tumor Microenvironemnt Penarete Acosta, Daniel Alfonso (2022-11-29)The colonic microbiota has been identified as a key player in the development of colorectal cancer. While changes in microbiota composition and function correlate with disease progression and treatment outcome, the mechanism ...
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Wang, Haoqi (2021-12-10)This dissertation presents an in-silico molecular-dynamic-simulation-based drug discovery tool and its utility to find inhibitors for pathogenic microorganisms. Specifically, the applicability of the tool has been demonstrated ...
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Barnes, Ryan Crispen (2016-11-10)The composition, absorption, metabolism, and excretion of gallic acid, monogalloyl glucose, and gallotannins in mango (Mangifera indica L.) pulp were investigated. Each galloyl derivative was hypothesized to have a different ...
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Huang, Mian (2017-05-10)Candida glabrata (C. glabrata) is an emerging opportunistic human fungal pathogen with an increasing incidence as the cause of both mucosal and systemic infections. In addition, the fungus is the most commonly used ...
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Reyes Barrios, Luis Humberto (2013-07-24)Microbial-based industrial production has experienced a revolutionary development in the last decades as chemical industry has shifted its focus towards more sustain- able production of fuels, building blocks for materials, ...
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Seely, Andrew Loran (2017-07-31)Escherichia coli senses a variety of chemoeffectors. The Tsr chemoreceptor is known to mediate attractant response to serine. Previously, serine was the only attractant described for Tsr. Recent work suggests Tsr senses ...
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Choi, KyungOh; Ghaddar, Bassel; Moya, Colby; Shi, Hai; Sridharan, Gautham V.; Lee, Kyongbum; Jayaraman, Arul; Chan, Christina (PloS One, 2014)
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Chaar, David; Nathan, Lakshmi; Nair, Pallavi; Hernandez, Selena (2013-02-27)Obesity and the metabolic diseases associated with it, such as diabetes and cardiovascular disease, are areas of major concern in the USA. Obesity is associated with low grade inflammation in adipose tissue; therefore, ...
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Kim, Sinae (Texas A&M University, 2007-09-17)The increased collection of high-dimensional data in various fields has raised a strong interest in clustering algorithms and variable selection procedures. In this disserta- tion, I propose a model-based method that ...
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Lee, Do Gyun (2012-10-19)Triclosan, a synthetic antimicrobial agent, is an emerging environmental contaminant. Due to incomplete removal of triclosan by wastewater treatment plants, treated wastewater is one major source of environmental triclosan. ...
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Guo, Shengchun (2018-05-04)Osteopontin (OPN) is a multifunctional protein presented in various organs and body fluids in human body. OPN serves important roles in bone remolding, wound healing, and other biomineralization related physiological ...
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Munjal, Neera (2014-12-03)The eukaryotic green alga, Chlamydomonas reinhardtii, is a unique expression platform that can efficiently express complex therapeutic proteins. However, demonstrating that therapeutic molecules can be produced in quantifiable ...
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Quinones, Katelyn (2015-08-11)The chloroplast of eukaryotic green algae, Chlamydomonas reinhardtii, is a relatively new and unexplored platform for the production of human therapeutics, vaccines, and human monoclonal antibodies. To accurately determine ...
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Purkayastha, Purboja (2022-08-29)Mechanical properties such as pressure, viscosity and substrate stiffness are inherent components of a cell's environment. Mammalian cells respond to such mechanical cues by altering their behavior. Mechano-responsive ...
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Guard, Blake C.; Barr, James W.; Reddivari, Lavanya; Klemashevich, Cory; Jayaraman, Arul; Steiner, Jörg M.; Vanamala, Jairam; Suchodolski, Jan S.; Monleon, Daniel (PloS One, 2015)
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Chamoun Emanuelli, Ana M (2014-08-06)Hepatitis C virus (HCV), Human Immunodeficiency virus (HIV) and Herpes Simplex virus (HSV) are pathogenic viruses known to cause liver disorder, acquired immunodeficiency and skin lesions, respectively. Although current ...
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Pasupuleti, Sasi Kiran (2017-12-11)The co-existence of ~1014 commensal bacteria and host cells in the human gastrointestinal (GI) tract creates an environment rich in molecules produced by both. The close-proximity of different signals and cells in the GI ...
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Jani, Sneha Jagdish (2017-05-08)Bacteria navigate within their environment in response to gradients of several environmental cues, including nutrients, toxins, pH, temperature and oxygen. Recent studies demonstrate that Escherichia coli also senses ...
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Vikram, Amit (2012-07-16)The secondary metabolites of citrus such as limonoids and flavonoids constitute an important part of human diet. The present work was undertaken to elucidate the effect of citrus limonoids and flavonoids on the bacterial ...