Browsing by Author "Hilty, Christian"
Now showing items 1-20 of 45
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Ogier, Stephen Edwin (2019-11-08)The introduction of receive arrays revolutionized ^1H MRI and in vivo NMR by increasing SNR and enabling accelerated imaging. All MRI scanners manufactured today are equipped to receive signals from ^1H array coils, but ...
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Lee, Youngbok (2013-03-13)Nuclear magnetic resonance (NMR) spectroscopy is one of the most important analytical tools for organic and biological chemistry. It provides not only detailed information on the structure of small molecules and macromolecules, ...
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Bowen, Sean Michael (2012-02-14)Nuclear magnetic resonance (NMR) yields remarkably detailed structural information about virtually any molecule. However, its application to non-equilibrium systems is hampered by a lack of sensitivity. To increase the ...
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Zhang, Guannan (2017-10-17)Nuclear magnetic resonance (NMR) spectroscopy is a powerful analytical technique for chemistry and biochemistry. Since an inherent limitation of NMR is a lack of sensitivity, long experimental time with signal averaging ...
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McCormick, Sean P. (2014-12-10)Eukaryotic cells contain low-molecular-mass metal complexes (LMMMCs), defined as having masses between 200 – 10,000 Da, but these so-called labile or chelatable metal pools are poorly defined in terms of structures and ...
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Pham, Pierce Phuc (2023-01-05)Nuclear magnetic resonance (NMR) spectroscopy is a popular analytic technique in chemistry despite its intrinsic, low sensitivity. Nuclear spin hyperpolarization methods can improve NMR signals by several orders of magnitude ...
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Mandal, Ratnamala (2021-12-07)Nuclear magnetic resonance (NMR) spectroscopy is a widespread analytical technique used to characterize intermolecular interactions. However, due to the inherent insensitivity of NMR, long experimental times and large ...
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Characterization of Olefin Polymerization Reactions Using Dissolution Dynamic Nuclear Polarization Chen, Chia-Hsiu (2018-08-31)NNuclear magnetic resonance (NMR) spectroscopy is a powerful analytical tool with widespread applications in all areas of synthetic chemistry including polymer chemistry. High-resolution solution-state NMR not only provides ...
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Kim, Jihyun (2020-07-17)Structural changes occurring during the folding and unfolding of proteins are not directly accessible with nuclear magnetic resonance (NMR) spectroscopy due to a slower timescale of detection compared to that of the folding ...
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Dewey, Jill Sayes (2011-10-21)Bacteriophage holins are a diverse group of proteins that are responsible for the spontaneous and specifically-timed triggering of host cell lysis. The best-studied holin, S105 of phage lambda, is known to form lesions, ...
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Skiles, Stephanie Lyn (2014-10-24)The increased development of surface science in the last half century has opened up new fields for exploration. Surfaces from the pristine to the complex can now be studied with relative ease. These developments along with ...
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Moore, D'Vesharronne J. (2012-07-16)An array of analytical methods including density gradient ultracentrifugation, capillary electrophoresis, and matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS), were utilized to analyze serum high ...
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Pham, Pierce; Hilty, Christian (2023-09-07)This entry contains data sets for Pham, P and Hilty, C. Biomolecular interactions studied by low-field NMR using SABRE hyperpolarization, Chem. Sci., 2023, DOI: 10.1039/D3SC02365F
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Jiang, Zhengyang (2019-05-21)Cancer has become one of the biggest threats to human health. In most cases, cancer cells can be differentiated from normal tissues via the overexpression of certain cellular membrane proteins. Improved therapeutic effects ...
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Ragavan, Mukundan (2014-06-27)Nuclear Magnetic Resonance (NMR) spectroscopy provides remarkable site resolution, but often requires signal averaging because of low sensitivity. Dissolution dynamic nuclear polarization (DNP), which offers large signal ...
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Xiao, Chunying (2015-10-02)The effects of charge states, charge sites and side chain interactions on conformational preferences of gas phase peptide ions are examined by ion mobility-mass spectrometry (IM-MS) and molecular dynamics (MD) simulations. ...
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Tharp II, Jeffery Micheal (2018-03-20)Phage display is a widely-used tool for the directed evolution of peptide ligands from large combinatorial peptide libraries. A limitation of this technique arises from the lack of chemical diversity of the phage-displayed ...
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Park, Jihye (2016-06-17)Metal–organic frameworks (MOFs) are newly emerging inorganic–organic hybrid porous materials with diverse crystalline structures, high surface areas, and tunable pores. This dissertation primarily focuses on design and ...
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Heo, Gyu Seong (2016-05-04)Microorganisms, including bacteria, viruses, fungi, or parasites, give rise to infectious diseases, which can spread between people, and can even transfer from animals or insects to humans. Infectious diseases are common, ...
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Chen, Liuxi (2012-10-19)Ion mobility spectrometry (IMS) separates ions on the basis of ion-neutral collision cross-sections (CCS, [omega]), which are determined by the geometry or conformation of the ions. The size-based IM separation can be ...