Surface proteins from gram-positive bacteria having highly conserved motifs and antibodies that recognize them

Simple item page
dc.contributor.assigneeThe Texas A & M Univerisity System
dc.creatorXu, Yi
dc.creatorHook, Magnus A. O.
dc.date.accessioned2019-06-17T17:01:44Z
dc.date.available2019-06-17T17:01:44Z
dc.date.filed2004-08-05
dc.date.issued2007-03-27
dc.description.abstractIsolated peptide sequences and proteins containing these sequences are provided which are useful in the prevention and treatment of infection caused by Gram-positive bacteria. The peptide sequences have been shown to be highly conserved motifs in the surface proteins of Gram-positive bacteria, and these consensus sequences include amino acid sequences such as LPXTG (SEQ ID NO:13), ALKTGKIDIIISGMTSTPERKK (SEQ ID NO:14), VEGAVVEKPVAEAYLKQN (SEQ ID NO:15), and EYAGVDIDLAKKIAK (SEQ ID NO:16). By virtue of the highly conserved regions, the sequences and the proteins including these sequences can be utilized to generate antibodies which can recognize these highly conserved motifs and the proteins containing them and thus be useful in the treatment or prevention of a wide range of infections caused by Gram-positive bacteria.en
dc.description.countryUS
dc.format.digitalOriginreformatted digitalen
dc.identifier.patentapplicationnumber10/911507
dc.identifier.urihttps://hdl.handle.net/1969.1/176839
dc.languageeng
dc.publisherUnited States. Patent and Trademark Office
dc.publisher.digitalTexas A&M University. Libraries
dc.rightsPublic Domain (No copyright - United States)en
dc.rights.urihttp://rightsstatements.org/vocab/NoC-US/1.0/
dc.subject.cpcprimaryC07K 14/31
dc.subject.cpcprimaryC07K 14/315
dc.subject.cpcprimaryC07K 14/3156
dc.subject.cpcprimaryC07K 16/1267
dc.subject.cpcprimaryA61K 39/00
dc.subject.cpcprimaryA61K 2039/505
dc.subject.cpcprimaryY10S 930/29
dc.subject.uspcother424/130.1
dc.subject.uspcother424/141.1
dc.subject.uspcother424/143.1
dc.subject.uspcother424/150.1
dc.subject.uspcother424/163.1
dc.subject.uspcother424/164.1
dc.subject.uspcother424/165.1
dc.subject.uspcother424/178.1
dc.subject.uspcother424/278.1
dc.subject.uspcother530/387.1
dc.subject.uspcprimary424/139.1
dc.titleSurface proteins from gram-positive bacteria having highly conserved motifs and antibodies that recognize themen
dc.typeUtility patenten

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
7195763.pdf
Size:
1.49 MB
Format:
Adobe Portable Document Format
Download

Collections

Texas A&M University Patents