dc.contributor.advisor | Connell, Brian T. | |
dc.creator | Kang, Jun Yong | |
dc.date.accessioned | 2010-01-20T21:15:08Z | |
dc.date.available | 2010-01-20T21:15:08Z | |
dc.date.created | 2008-12 | |
dc.date.issued | 2010-01-20 | |
dc.identifier.uri | https://hdl.handle.net/1969.1/ETD-TAMU-2008-12-82 | |
dc.description.abstract | A new synthetic method toward 5-substituted isoxazolidines by [3 plus 2]
cycloaddition of nitrones generated from nitrosobenzene and styrene was discovered.
The formation of nitrones from nitrosobenzene and mono-substituted aromatic
styrenes was demonstrated. The cycloaddition reactions between styrenes and
nitrosobenzenes work well when a moderate excess of styrenes was employed. The
labeling studies support that cleavage of the styrene double bond occurred and accounted
for all the carbons in the starting materials and products.
A [3 plus 2] dipolar cycloaddition is implicated by the available mechanistic data and
allows for the rapid assembly of various substituted isoxazolidines directly from
nitrosobenzenes, electron deficient alkenes, and styrene. | en |
dc.format.mimetype | application/pdf | |
dc.language.iso | en_US | |
dc.subject | [3+2] dipolar cycloaddition | en |
dc.subject | isoxazolidine | en |
dc.subject | nitrone | en |
dc.title | Synthesis of 5-Substituted Isoxazolidines by [3 plus 2] Cycloaddition of Nitrones Generated in an Unusual Way from Nitrosobenzene and Styrene | en |
dc.type | Book | en |
dc.type | Thesis | en |
thesis.degree.department | Chemistry | en |
thesis.degree.discipline | Chemistry | en |
thesis.degree.grantor | Texas A&M University | en |
thesis.degree.name | Master of Science | en |
thesis.degree.level | Masters | en |
dc.contributor.committeeMember | Romo, Daniel | |
dc.contributor.committeeMember | Burgess, Kevin | |
dc.type.genre | Electronic Thesis | en |