The effects of the trol4 and trols1 mutations on neural stem cell development and proliferation in Drosophila melanogaster embryos
Abstract
The locus terribly reduced optic lobes or trol, is an X-linked homeobox gene involved in the control of neuroblast proliferation in Drosophila melanogaster larvae. It is known that trol acts in a pathway to counteract cell cycle repressors via the induction of cyclin E expression. The goal of the project is to use immunohistochemical methods to attempt to establish a phenotype for trol in the embryonic stage of development. Using the anti-engrailed and anti-fasciclin III antibodies, the developing nervous system can be examined for physical differences between different alleles and the wildtype embryos.
Description
Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to digital@library.tamu.edu, referencing the URI of the item.Includes bibliographical references (leaves 20-21).
Citation
Atkins, Mardelle Renee (2000). The effects of the trol4 and trols1 mutations on neural stem cell development and proliferation in Drosophila melanogaster embryos. Texas A&M University. Available electronically from https : / /hdl .handle .net /1969 .1 /ETD -TAMU -2000 -Fellows -Thesis -A87.