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The biological versus psychological basis of fatigue in depression
| dc.creator | Coscio, Stacey Aileen | |
| dc.date.accessioned | 2012-06-07T22:31:04Z | |
| dc.date.available | 2012-06-07T22:31:04Z | |
| dc.date.created | 1993 | |
| dc.date.issued | 1993 | |
| dc.identifier.uri | https://hdl.handle.net/1969.1/ETD-TAMU-1993-THESIS-C834 | |
| dc.description | Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to digital@library.tamu.edu, referencing the URI of the item. | en |
| dc.description | Includes bibliographical references. | en |
| dc.description.abstract | The objective of this study was to attempt to determine if the symptom of fatigue represents a metabolically induced or a perceived component in depressed individuals. Dietary intake patterns were analyzed for 20 depressed individuals to identify nutritional adequacy and the relationship which exists between diet and fatigue. A double blind sugar challenge was conducted to assess the mood altering effect of sugar. After baseline data were gathered, the subject was randomly assigned to consume either a sugar or acesulfame-K sweetened drink. The subject was asked to complete a series of mood scales and blood glucose was monitored every 30 minutes for 2 hours to assess the biological and psychological effects of the sugar. Results of the diet analysis revealed that the depressed male and female subjects had nutritional deficiencies when compared to the Recommended Daily Allowances and the Food Guide Pyramid. These nutritional deficiencies were in calcium, selenium, molybdenum, biotin, vitamin D, iodine, vitamin K, fluoride, and the milk, vegetable, and fruit food groups. Analysis of the blood glucose values following sugar ingestion, using two way classification repeated measures analysis of variance revealed significant effects of condition, time, and interaction of time and condition on blood glucose. Also blood glucose values indicated impaired glucose tolerance. Each of the POMS, PANAS, and EAS mood scales, analyzed by a two way classification repeated measures analysis of variance, revealed a nonsignificant difference for the main effect of condition and condition by time interaction but a significant time effect. The time main effect revealed that subjects' mood improved across time. The interaction effect for the POMS fatigue and anger scale scores approached significance and revealed a rapid decline in the scale scores following sugar consumption. These results indicate nutritional deficiencies in depressed subjects and impaired glucose tolerance which suggests that the fatigue in depressed individuals may be metabolically induced. | en |
| dc.format.medium | electronic | en |
| dc.format.mimetype | application/pdf | |
| dc.language.iso | en_US | |
| dc.publisher | Texas A&M University | |
| dc.rights | This thesis was part of a retrospective digitization project authorized by the Texas A&M University Libraries in 2008. Copyright remains vested with the author(s). It is the user's responsibility to secure permission from the copyright holder(s) for re-use of the work beyond the provision of Fair Use. | en |
| dc.subject | nutrition. | en |
| dc.subject | Major nutrition. | en |
| dc.title | The biological versus psychological basis of fatigue in depression | en |
| dc.type | Thesis | en |
| thesis.degree.discipline | nutrition | en |
| thesis.degree.name | M.S. | en |
| thesis.degree.level | Masters | en |
| dc.type.genre | thesis | en |
| dc.type.material | text | en |
| dc.format.digitalOrigin | reformatted digital | en |
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